Gene: ENSG00000223443 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000223443
Transcript Identifier
ENST00000333796
Gene Type
Coding gene
Location
8 : 12137168-12138760 : negative

Family Information

Homologous gene family
HOM03P000084
(314 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P002414
(30 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
ubiquitin specific peptidase 17-like family member 2

Identifiers

Type Value
pidENSP00000333329
HGNC34434
UniprotQ6R6M4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000075
IMP
Genome Projectcell cycle checkpoint
GO:0006508
IEA
Genome Projectproteolysis
GO:0006511
IEA
Genome Projectubiquitin-dependent protein catabolic process
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007049
IEA
Genome Projectcell cycle
GO:0007093
IMP
Genome Projectmitotic cell cycle checkpoint
GO:0010955
IMP
Genome Projectnegative regulation of protein processing
GO:0016579
IDA
Genome Projectprotein deubiquitination
GO:0030334
IMP
Genome Projectregulation of cell migration
GO:0031064
IMP
Genome Projectnegative regulation of histone deacetylation
GO:0034260
IDA
Genome Projectnegative regulation of GTPase activity
GO:0042127
IMP
Genome Projectregulation of cell proliferation
GO:0042981
IMP
Genome Projectregulation of apoptotic process
GO:0043161
IBA
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547
IMP
Genome Projectpositive regulation of GTPase activity
GO:0050691
IMP
Genome Projectregulation of defense response to virus by host
GO:0061136
IBA
Genome Projectregulation of proteasomal protein catabolic process
GO:0070536
IDA, IMP
Genome Projectprotein K63-linked deubiquitination
GO:0071108
IMP
Genome Projectprotein K48-linked deubiquitination
GO:0071586
IMP
Genome ProjectCAAX-box protein processing
GO:0090315
IMP
Genome Projectnegative regulation of protein targeting to membrane
GO:1900027
IMP
Genome Projectregulation of ruffle assembly
GO:1900245
IMP
Genome Projectpositive regulation of MDA-5 signaling pathway
GO:1900246
IMP
Genome Projectpositive regulation of RIG-I signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004197
IBA
Genome Projectcysteine-type endopeptidase activity
GO:0004843
IDA, IMP
Genome Projectubiquitin-specific protease activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008233
IEA
Genome Projectpeptidase activity
GO:0008234
IEA
Genome Projectcysteine-type peptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0036459
IEA
Genome Projectubiquitinyl hydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IDA
Genome Projectendoplasmic reticulum membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001394Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR018200Ubiquitin specific protease, conserved site
IPR028889Ubiquitin specific protease domain

No MapMan annotations defined for this gene.