Gene: ENSG00000222028 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000222028
Transcript Identifier
ENST00000408907
Gene Type
Coding gene
Location
14 : 23042226-23043128 : positive

Family Information

Homologous gene family
HOM03P000875
(67 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P070881
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
proteasome (prosome, macropain) subunit, beta type, 11

Identifiers

Type Value
pidENSP00000386212
HGNC31963
UniprotA5LHX3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000209
TAS
Genome Projectprotein polyubiquitination
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0002474
TAS
Genome Projectantigen processing and presentation of peptide antigen via MHC class I
GO:0002479
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0006508
IEA
Genome Projectproteolysis
GO:0006521
TAS
Genome Projectregulation of cellular amino acid metabolic process
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006977
TAS
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467
TAS
Genome Projectgene expression
GO:0010499
IBA
Genome Projectproteasomal ubiquitin-independent protein catabolic process
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0016032
TAS
Genome Projectviral process
GO:0031145
TAS
Genome Projectanaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641
TAS
Genome Projectcellular nitrogen compound metabolic process
GO:0042590
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981
TAS
Genome Projectregulation of apoptotic process
GO:0043066
TAS
Genome Projectnegative regulation of apoptotic process
GO:0043161
IBA
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0051437
TAS
Genome Projectpositive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
GO:0051439
TAS
Genome Projectregulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603
IEA
Genome Projectproteolysis involved in cellular protein catabolic process
GO:0090090
TAS
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090263
TAS
Genome Projectpositive regulation of canonical Wnt signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004175
IBA
IEA
Genome Projectendopeptidase activity
GO:0004298
IEA
Genome Projectthreonine-type endopeptidase activity
GO:0008233
IEA
Genome Projectpeptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000502
IEA
Genome Projectproteasome complex
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IBA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005839
IBA
IEA
Genome Projectproteasome core complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000243Peptidase T1A, proteasome beta-subunit
IPR001353Proteasome, subunit alpha/beta
IPR016050Proteasome beta-type subunit, conserved site
IPR023333Proteasome B-type subunit
IPR029055Nucleophile aminohydrolases, N-terminal

No MapMan annotations defined for this gene.