Gene: ENSG00000221866 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000221866
Transcript Identifier
ENST00000359827
Gene Type
Coding gene
Location
7 : 132130479-132508693 : negative

Family Information

Homologous gene family
HOM03P006231
(14 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P007566
(11 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
plexin A4

Identifiers

Type Value
pidENSP00000352882
HGNC9102
UniprotQ9HCM2
UniprotA0A024R7A6

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007399
IEA
Genome Projectnervous system development
GO:0007411
TAS, IEA
Genome Projectaxon guidance
GO:0008045
IEA
Genome Projectmotor neuron axon guidance
GO:0021602
IEA
Genome Projectcranial nerve morphogenesis
GO:0021610
IEA
Genome Projectfacial nerve morphogenesis
GO:0021612
IEA
Genome Projectfacial nerve structural organization
GO:0021615
IEA
Genome Projectglossopharyngeal nerve morphogenesis
GO:0021636
IEA
Genome Projecttrigeminal nerve morphogenesis
GO:0021637
IEA
Genome Projecttrigeminal nerve structural organization
GO:0021644
IEA
Genome Projectvagus nerve morphogenesis
GO:0021784
IEA
Genome Projectpostganglionic parasympathetic fiber development
GO:0021785
IEA
Genome Projectbranchiomotor neuron axon guidance
GO:0021793
IEA
Genome Projectchemorepulsion of branchiomotor axon
GO:0021960
IEA
Genome Projectanterior commissure morphogenesis
GO:0048485
IEA
Genome Projectsympathetic nervous system development
GO:0048812
IEA
Genome Projectneuron projection morphogenesis
GO:0048841
IEA
Genome Projectregulation of axon extension involved in axon guidance
GO:0050923
IEA
Genome Projectregulation of negative chemotaxis
GO:0071526
NAS, IEA
Genome Projectsemaphorin-plexin signaling pathway
GO:1902287
IEA
Genome Projectsemaphorin-plexin signaling pathway involved in axon guidance

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0017154
IEA
Genome Projectsemaphorin receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0002116
TAS
Genome Projectsemaphorin receptor complex
GO:0005886
TAS, IEA
Genome Projectplasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001627Sema domain
IPR002165Plexin repeat
IPR002909IPT domain
IPR008936Rho GTPase activation protein
IPR013548Plexin, cytoplasmic RasGAP domain
IPR013783Immunoglobulin-like fold
IPR014756Immunoglobulin E-set
IPR015943WD40/YVTN repeat-like-containing domain
IPR016201Plexin-like fold
IPR031148Plexin family

No MapMan annotations defined for this gene.