Gene: ENSG00000206340 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000206340
Transcript Identifier
ENST00000383325
Gene Type
Coding gene
Location
CHR_HSCHR6_MHC_QBL_CTG1 : 3238079-3258512 : positive

Family Information

Homologous gene family
HOM03P002669
(35 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P006383
(13 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
complement component 4A (Rodgers blood group)

Identifiers

Type Value
pidENSP00000372815
HGNC1323
UniprotP0C0L4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002376
IEA
Genome Projectimmune system process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0006956
IGI
TAS, IEA
Genome Projectcomplement activation
GO:0006958
IEA
Genome Projectcomplement activation, classical pathway
GO:0010951
IEA
Genome Projectnegative regulation of endopeptidase activity
GO:0030449
TAS
Genome Projectregulation of complement activation
GO:0045087
TAS, IEA
Genome Projectinnate immune response
GO:2000427
IGI
Genome Projectpositive regulation of apoptotic cell clearance

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001849
IDA
Genome Projectcomplement component C1q binding
GO:0004866
IEA
Genome Projectendopeptidase inhibitor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005886
TAS
Genome Projectplasma membrane
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0072562
IDA
Genome Projectblood microparticle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000020Anaphylatoxin/fibulin
IPR001134Netrin domain
IPR001599Alpha-2-macroglobulin
IPR001840Anaphylatoxin, complement system domain
IPR002890Alpha-2-macroglobulin, N-terminal
IPR008930Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
IPR008993Tissue inhibitor of metalloproteinases-like, OB-fold
IPR009048Alpha-macroglobulin, receptor-binding
IPR011625Alpha-2-macroglobulin, N-terminal 2
IPR011626Alpha-macroglobulin complement component
IPR018081Anaphylatoxin, complement system
IPR018933Netrin module, non-TIMP type
IPR019565Alpha-2-macroglobulin, thiol-ester bond-forming
IPR019742Alpha-2-macroglobulin, conserved site

No MapMan annotations defined for this gene.