Gene: ENSG00000204580 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000204580
Transcript Identifier
ENST00000513240
Gene Type
Coding gene
Location
6 : 30888730-30899296 : positive

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P008919
(9 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
discoidin domain receptor tyrosine kinase 1

Identifiers

Type Value
pidENSP00000427552
HGNC2730
UniprotQ08345
UniprotA0A024RCJ0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001558
IEA
Genome Projectregulation of cell growth
GO:0001952
IEA
Genome Projectregulation of cell-matrix adhesion
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007169
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007566
IEA
Genome Projectembryo implantation
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0018108
IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0031100
IEA
Genome Projectorgan regeneration
GO:0038063
IEA
Genome Projectcollagen-activated tyrosine kinase receptor signaling pathway
GO:0043583
IEA
Genome Projectear development
GO:0043588
IEA
Genome Projectskin development
GO:0060444
IEA
Genome Projectbranching involved in mammary gland duct morphogenesis
GO:0060749
IEA
Genome Projectmammary gland alveolus development

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004714
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0038062
IEA
Genome Projectprotein tyrosine kinase collagen receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005887
IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016323
IEA
Genome Projectbasolateral plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000421Coagulation factor 5/8 C-terminal domain
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002011Tyrosine-protein kinase, receptor class II, conserved site
IPR008266Tyrosine-protein kinase, active site
IPR008979Galactose-binding domain-like
IPR011009Protein kinase-like domain
IPR020635Tyrosine-protein kinase, catalytic domain
IPR029553Discoidin domain-containing receptor

No MapMan annotations defined for this gene.