Gene: ENSG00000198886 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000198886
Transcript Identifier
ENST00000361381
Gene Type
Coding gene
Location
MT : 10760-12137 : positive

Family Information

Homologous gene family
HOM03P122859
(orphan gene)
specific family

Descriptions

gene_descr
mitochondrially encoded NADH dehydrogenase 4

Identifiers

Type Value
pidENSP00000354961
HGNC7459
UniprotP03905
UniprotH9EC08

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0006120
NAS, IEA
Genome Projectmitochondrial electron transport, NADH to ubiquinone
GO:0007568
IEA
Genome Projectaging
GO:0021549
IEA
Genome Projectcerebellum development
GO:0035094
IEA
Genome Projectresponse to nicotine
GO:0042773
IEA
Genome ProjectATP synthesis coupled electron transport
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0022904
TAS
Genome Projectrespiratory electron transport chain
GO:0044237
TAS
Genome Projectcellular metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008137
NAS, IEA
Genome ProjectNADH dehydrogenase (ubiquinone) activity
GO:0016491
IEA
Genome Projectoxidoreductase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IEA
Genome Projectmitochondrion
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031966
IEA
Genome Projectmitochondrial membrane
GO:0070469
IEA
Genome Projectrespiratory chain
GO:0005743
TAS
Genome Projectmitochondrial inner membrane
GO:0005747
IDA
NAS
Genome Projectmitochondrial respiratory chain complex I

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000260NADH:ubiquinone oxidoreductase chain 4, N-terminal
IPR001750NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit
IPR003918NADH:ubiquinone oxidoreductase
IPR010227NADH-quinone oxidoreductase, chain M/4

No MapMan annotations defined for this gene.