Gene: ENSG00000197594 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000197594
Transcript Identifier
ENST00000360971
Gene Type
Coding gene
Location
6 : 131808036-131890511 : positive

Family Information

Homologous gene family
HOM03P002888
(33 genes in 13 species)
specific family
Orthologous gene family
ORTHO03P004009
(21 genes in 13 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
ectonucleotide pyrophosphatase/phosphodiesterase 1

Identifiers

Type Value
pidENSP00000354238
HGNC3356
UniprotP22413

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006091
IDA
Genome Projectgeneration of precursor metabolites and energy
GO:0006766
TAS
Genome Projectvitamin metabolic process
GO:0006767
TAS
Genome Projectwater-soluble vitamin metabolic process
GO:0006771
TAS
Genome Projectriboflavin metabolic process
GO:0006796
IDA
Genome Projectphosphate-containing compound metabolic process
GO:0006898
IEA
Genome Projectreceptor-mediated endocytosis
GO:0006955
IEA
Genome Projectimmune response
GO:0008152
IEA
Genome Projectmetabolic process
GO:0009143
IDA
Genome Projectnucleoside triphosphate catabolic process
GO:0030279
IEA
Genome Projectnegative regulation of ossification
GO:0030308
IDA
Genome Projectnegative regulation of cell growth
GO:0030500
IC
Genome Projectregulation of bone mineralization
GO:0030505
IDA
Genome Projectinorganic diphosphate transport
GO:0030643
IDA
Genome Projectcellular phosphate ion homeostasis
GO:0030730
IDA
Genome Projectsequestering of triglyceride
GO:0031214
IEA
Genome Projectbiomineral tissue development
GO:0031953
IDA
Genome Projectnegative regulation of protein autophosphorylation
GO:0032869
IDA
Genome Projectcellular response to insulin stimulus
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045599
IDA
Genome Projectnegative regulation of fat cell differentiation
GO:0045719
IDA
Genome Projectnegative regulation of glycogen biosynthetic process
GO:0046325
IDA
Genome Projectnegative regulation of glucose import
GO:0046627
IDA
Genome Projectnegative regulation of insulin receptor signaling pathway
GO:0046849
IEA
Genome Projectbone remodeling
GO:0050427
IDA
Genome Project3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO:0090305
ISS
IEA
Genome Projectnucleic acid phosphodiester bond hydrolysis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004528
ISS
IEA
Genome Projectphosphodiesterase I activity
GO:0004551
IDA
TAS, IEA
Genome Projectnucleotide diphosphatase activity
GO:0005044
IEA
Genome Projectscavenger receptor activity
GO:0005158
IDA
Genome Projectinsulin receptor binding
GO:0005509
ISS
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IDA
Genome ProjectATP binding
GO:0008270
ISS
Genome Projectzinc ion binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0030247
IEA
Genome Projectpolysaccharide binding
GO:0035529
IEA
Genome ProjectNADH pyrophosphatase activity
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0047429
IDA
Genome Projectnucleoside-triphosphate diphosphatase activity
GO:0050656
IC
Genome Project3'-phosphoadenosine 5'-phosphosulfate binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
Genome Projectextracellular space
GO:0005765
IDA
Genome Projectlysosomal membrane
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
ISS
Genome Projectintegral component of plasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
ISS
TAS, IEA
Genome Projectintegral component of membrane
GO:0016323
NAS, IEA
Genome Projectbasolateral plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001212Somatomedin B domain
IPR001604DNA/RNA non-specific endonuclease
IPR002591Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
IPR017849Alkaline phosphatase-like, alpha/beta/alpha
IPR017850Alkaline-phosphatase-like, core domain
IPR020436Somatomedin B, chordata
IPR020821Extracellular Endonuclease, subunit A
IPR024873Ectonucleotide pyrophosphatase/phosphodiesterase family
IPR029890Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

No MapMan annotations defined for this gene.