Gene: ENSG00000197579 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000197579
Transcript Identifier
ENST00000360538
Gene Type
Coding gene
Location
9 : 32541387-32552436 : negative

Family Information

Homologous gene family
HOM03P005521
(16 genes in 13 species)
specific family
Orthologous gene family
ORTHO03P062804
(2 genes in 2 species)
specific family

Descriptions

gene_descr
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase

Identifiers

Type Value
pidENSP00000353735
HGNC21653
UniprotQ9NS56

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006351
NAS
Genome Projecttranscription, DNA-templated
GO:0006511
IMP
Genome Projectubiquitin-dependent protein catabolic process
GO:0006513
IDA
Genome Projectprotein monoubiquitination
GO:0006974
IDA
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0008630
IDA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0010842
ISS
Genome Projectretina layer formation
GO:0016925
IDA, IMP
Genome Projectprotein sumoylation
GO:0034504
IMP
Genome Projectprotein localization to nucleus
GO:0035845
ISS
Genome Projectphotoreceptor cell outer segment organization
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0042771
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043066
ISS
Genome Projectnegative regulation of apoptotic process
GO:0043161
IMP
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0046548
ISS
Genome Projectretinal rod cell development
GO:0046549
ISS
Genome Projectretinal cone cell development
GO:0051443
IDA
Genome Projectpositive regulation of ubiquitin-protein transferase activity
GO:0051457
IDA
Genome Projectmaintenance of protein location in nucleus
GO:0070936
IDA
Genome Projectprotein K48-linked ubiquitination

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IDA
Genome ProjectDNA binding
GO:0003823
IPI
Genome Projectantigen binding
GO:0004842
IDA, IMP
Genome Projectubiquitin-protein transferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0016874
IEA
Genome Projectligase activity
GO:0019789
IDA, IMP
Genome ProjectSUMO transferase activity
GO:0044547
IPI
Genome ProjectDNA topoisomerase binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0061630
IDA
Genome Projectubiquitin protein ligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000151
IDA
Genome Projectubiquitin ligase complex
GO:0000922
IDA
Genome Projectspindle pole
GO:0000930
IDA
Genome Projectgamma-tubulin complex
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005814
IDA
Genome Projectcentriole
GO:0016605
IDA
IEA
Genome ProjectPML body
GO:0016607
IDA
Genome Projectnuclear speck
GO:0030496
TAS
Genome Projectmidbody
GO:0032391
IDA
Genome Projectphotoreceptor connecting cilium
GO:0036064
IDA
Genome Projectciliary basal body
GO:0005868
TAS
Genome Projectcytoplasmic dynein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR017907Zinc finger, RING-type, conserved site

No MapMan annotations defined for this gene.