Gene: ENSG00000197548 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000197548
Transcript Identifier
ENST00000354449
Gene Type
Coding gene
Location
3 : 11298696-11554843 : positive

Family Information

Homologous gene family
HOM03P002448
(37 genes in 36 species)
specific family

Descriptions

gene_descr
autophagy related 7

Identifiers

Type Value
pidENSP00000346437
HGNC16935
UniprotO95352

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000422
IBA
Genome Projectmitophagy
GO:0001889
IEA
Genome Projectliver development
GO:0006464
TAS
Genome Projectcellular protein modification process
GO:0006497
IDA
Genome Projectprotein lipidation
GO:0006501
IBA
Genome ProjectC-terminal protein lipidation
GO:0006520
IEA
Genome Projectcellular amino acid metabolic process
GO:0006810
IEA
Genome Projecttransport
GO:0006914
IEA
Genome Projectautophagy
GO:0006995
IBA
Genome Projectcellular response to nitrogen starvation
GO:0006996
IEA
Genome Projectorganelle organization
GO:0007005
IEA
Genome Projectmitochondrion organization
GO:0007628
IEA
Genome Projectadult walking behavior
GO:0009267
IDA
Genome Projectcellular response to starvation
GO:0009791
IEA
Genome Projectpost-embryonic development
GO:0010508
IMP
Genome Projectpositive regulation of autophagy
GO:0015031
IEA
Genome Projectprotein transport
GO:0016236
IBA
Genome Projectmacroautophagy
GO:0016239
IMP
Genome Projectpositive regulation of macroautophagy
GO:0016567
TAS
Genome Projectprotein ubiquitination
GO:0021680
IEA
Genome Projectcerebellar Purkinje cell layer development
GO:0021860
IEA
Genome Projectpyramidal neuron development
GO:0021955
IEA
Genome Projectcentral nervous system neuron axonogenesis
GO:0021987
IEA
Genome Projectcerebral cortex development
GO:0030163
IBA
IEA
Genome Projectprotein catabolic process
GO:0031175
IEA
Genome Projectneuron projection development
GO:0031396
IEA
Genome Projectregulation of protein ubiquitination
GO:0031401
IDA
IEA
Genome Projectpositive regulation of protein modification process
GO:0032446
IBA
IEA
Genome Projectprotein modification by small protein conjugation
GO:0034727
IBA
Genome Projectpiecemeal microautophagy of nucleus
GO:0039521
IMP
Genome Projectsuppression by virus of host autophagy
GO:0039689
IEA
Genome Projectnegative stranded viral RNA replication
GO:0042594
IEA
Genome Projectresponse to starvation
GO:0043065
IMP
Genome Projectpositive regulation of apoptotic process
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0044805
IBA
Genome Projectlate nucleophagy
GO:0045732
IMP
Genome Projectpositive regulation of protein catabolic process
GO:0050877
IEA
Genome Projectneurological system process
GO:0051607
IMP
Genome Projectdefense response to virus
GO:0055013
IEA
Genome Projectcardiac muscle cell development
GO:0061024
IEA
Genome Projectmembrane organization
GO:0061025
TAS
Genome Projectmembrane fusion
GO:0070257
IEA
Genome Projectpositive regulation of mucus secretion
GO:0071455
IDA
Genome Projectcellular response to hyperoxia
GO:1903146
IGI
Genome Projectregulation of mitophagy
GO:2000619
IEA
Genome Projectnegative regulation of histone H4-K16 acetylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004839
TAS
Genome Projectubiquitin activating enzyme activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0008641
IEA
Genome Projectsmall protein activating enzyme activity
GO:0019778
ISS, IBA
IEA
Genome ProjectAtg12 activating enzyme activity
GO:0019779
IBA
IEA
Genome ProjectAtg8 activating enzyme activity
GO:0042803
IDA
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000407
IBA
IEA
Genome Projectpre-autophagosomal structure
GO:0005737
IDA
TAS, IEA
Genome Projectcytoplasm
GO:0005829
IBA
Genome Projectcytosol
GO:0005930
ISS
Genome Projectaxoneme

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000594THIF-type NAD/FAD binding fold
IPR006285Ubiquitin-like modifier-activating enzyme Atg7
IPR032197Ubiquitin-like modifier-activating enzyme Atg7, N-terminal

No MapMan annotations defined for this gene.