Gene: ENSG00000196632 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000196632
Transcript Identifier
ENST00000375159
Gene Type
Coding gene
Location
X : 54198324-54333673 : negative

Family Information

Homologous gene family
HOM03P000549
(90 genes in 34 species)
specific family

Descriptions

gene_descr
WNK lysine deficient protein kinase 3

Identifiers

Type Value
pidENSP00000364301
HGNC14543
UniprotQ9BYP7

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
ISS
IEA
Genome Projectprotein phosphorylation
GO:0010765
IDA
Genome Projectpositive regulation of sodium ion transport
GO:0010800
IDA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0032414
IDA
Genome Projectpositive regulation of ion transmembrane transporter activity
GO:0035556
ISS
Genome Projectintracellular signal transduction
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0046777
IDA
Genome Projectprotein autophosphorylation
GO:0051928
IMP
Genome Projectpositive regulation of calcium ion transport
GO:0090004
IDA
Genome Projectpositive regulation of establishment of protein localization to plasma membrane
GO:2000021
IMP
Genome Projectregulation of ion homeostasis
GO:2000651
IDA, IMP
Genome Projectpositive regulation of sodium ion transmembrane transporter activity
GO:2000682
IDA
Genome Projectpositive regulation of rubidium ion transport
GO:2000688
IDA
Genome Projectpositive regulation of rubidium ion transmembrane transporter activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
ISS
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
ISS
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019869
IDA
Genome Projectchloride channel inhibitor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005912
ISS
IEA
Genome Projectadherens junction
GO:0005923
ISS
IEA
Genome Projectbicellular tight junction

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR024678Serine/threonine-protein kinase OSR1/WNK, CCT domain

No MapMan annotations defined for this gene.