Gene: ENSG00000196549 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000196549
Transcript Identifier
ENST00000615825
Gene Type
Coding gene
Location
3 : 155084168-155180459 : positive

Family Information

Homologous gene family
HOM03P000874
(67 genes in 14 species)
specific family

Descriptions

gene_descr
membrane metallo-endopeptidase

Identifiers

Type Value
pidENSP00000478173
HGNC7154
UniprotP08473

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001822
IEP
Genome Projectkidney development
GO:0002003
TAS
Genome Projectangiotensin maturation
GO:0006508
IDA
IEA
Genome Projectproteolysis
GO:0006518
ISS
Genome Projectpeptide metabolic process
GO:0019233
ISS
IEA
Genome Projectsensory perception of pain
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0046449
IMP
Genome Projectcreatinine metabolic process
GO:0050435
ISS
IEA
Genome Projectbeta-amyloid metabolic process
GO:0071345
IDA
Genome Projectcellular response to cytokine stimulus
GO:0071492
IDA
Genome Projectcellular response to UV-A
GO:0071493
IDA
Genome Projectcellular response to UV-B
GO:0090399
IEP
Genome Projectreplicative senescence

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004175
IDA, IMP
Genome Projectendopeptidase activity
GO:0004222
IDA, IMP
IEA
Genome Projectmetalloendopeptidase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008233
IEA
Genome Projectpeptidase activity
GO:0008237
IEA
Genome Projectmetallopeptidase activity
GO:0008238
IDA
Genome Projectexopeptidase activity
GO:0008270
IDA
Genome Projectzinc ion binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0042277
ISS
Genome Projectpeptide binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
NAS
Genome Projectintegral component of plasma membrane
GO:0005903
IDA
Genome Projectbrush border
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0008021
ISS
IEA
Genome Projectsynaptic vesicle
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
NAS, IEA
Genome Projectintegral component of membrane
GO:0030424
ISS
IEA
Genome Projectaxon
GO:0030425
ISS
IEA
Genome Projectdendrite
GO:0044306
ISS
IEA
Genome Projectneuron projection terminus
GO:0045202
ISS
IEA
Genome Projectsynapse
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000718Peptidase M13
IPR008753Peptidase M13, N-terminal domain
IPR018497Peptidase M13, C-terminal domain
IPR024079Metallopeptidase, catalytic domain
IPR029727Neprilysin

No MapMan annotations defined for this gene.