Gene: ENSG00000196419 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000196419
Transcript Identifier
ENST00000405878
Gene Type
Coding gene
Location
22 : 41622005-41663815 : positive

Family Information

Homologous gene family
HOM03P003096
(31 genes in 27 species)
specific family
Orthologous gene family
ORTHO03P002739
(28 genes in 25 species)
specific family

Descriptions

gene_descr
X-ray repair complementing defective repair in Chinese hamster cells 6

Identifiers

Type Value
pidENSP00000384257
HGNC4055
UniprotP12956
UniprotA0A024R1N4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000723
TAS, IEA
Genome Projecttelomere maintenance
GO:0006303
IMP
TAS, IEA
Genome Projectdouble-strand break repair via nonhomologous end joining
GO:0032508
TAS, IEA
Genome ProjectDNA duplex unwinding
GO:0006266
TAS
Genome ProjectDNA ligation
GO:0006281
TAS, IEA
Genome ProjectDNA repair
GO:0006302
TAS
Genome Projectdouble-strand break repair
GO:0006310
IEA
Genome ProjectDNA recombination
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0008152
IEA
Genome Projectmetabolic process
GO:0016032
TAS
Genome Projectviral process
GO:0032481
TAS
Genome Projectpositive regulation of type I interferon production
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045892
IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA, IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048660
IMP
Genome Projectregulation of smooth muscle cell proliferation
GO:0075713
TAS
Genome Projectestablishment of integrated proviral latency

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
NAS, IEA
Genome ProjectDNA binding
GO:0003684
IEA
Genome Projectdamaged DNA binding
GO:0004003
TAS, IEA
Genome ProjectATP-dependent DNA helicase activity
GO:0042162
IEA
Genome Projecttelomeric DNA binding
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003690
TAS
Genome Projectdouble-stranded DNA binding
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004386
IEA
Genome Projecthelicase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016829
IEA
Genome Projectlyase activity
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0051575
IMP
Genome Project5'-deoxyribose-5-phosphate lyase activity
GO:0003691
IDA
Genome Projectdouble-stranded telomeric DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
TAS, IEA
Genome Projectnucleus
GO:0043564
IDA
IEA
Genome ProjectKu70:Ku80 complex
GO:0000783
TAS
Genome Projectnuclear telomere cap complex
GO:0000784
IDA
Genome Projectnuclear chromosome, telomeric region
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005667
IDA
Genome Projecttranscription factor complex
GO:0005694
IEA
Genome Projectchromosome
GO:0005829
TAS
Genome Projectcytosol
GO:0016020
IDA
TAS
Genome Projectmembrane
GO:0070419
IDA
Genome Projectnonhomologous end joining complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002035von Willebrand factor, type A
IPR003034SAP domain
IPR005160Ku70/Ku80 C-terminal arm
IPR005161Ku70/Ku80, N-terminal alpha/beta
IPR006164Ku70/Ku80 beta-barrel domain
IPR006165Ku70
IPR016194SPOC-like, C-terminal domain
IPR027388Ku70, bridge and pillars domain

No MapMan annotations defined for this gene.