Gene: ENSG00000196405 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000196405
Transcript Identifier
ENST00000392920
Gene Type
Coding gene
Location
14 : 100065501-100143738 : positive

Family Information

Homologous gene family
HOM03P010257
(8 genes in 5 species)
specific family
Orthologous gene family
ORTHO03P074396
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
Enah/Vasp-like

Identifiers

Type Value
pidENSP00000376652
HGNC20234
UniprotQ9UI08

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007015
TAS
Genome Projectactin filament organization
GO:0007166
NAS
Genome Projectcell surface receptor signaling pathway
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0007399
NAS
Genome Projectnervous system development
GO:0007411
TAS
Genome Projectaxon guidance
GO:0008154
ISS
IEA
Genome Projectactin polymerization or depolymerization
GO:0009887
NAS
Genome Projectorgan morphogenesis
GO:0010633
IMP
Genome Projectnegative regulation of epithelial cell migration
GO:0030838
IEA
Genome Projectpositive regulation of actin filament polymerization
GO:0051289
IEA
Genome Projectprotein homotetramerization
GO:0051496
IMP
Genome Projectpositive regulation of stress fiber assembly
GO:1900028
IMP
Genome Projectnegative regulation of ruffle assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003779
IEA
Genome Projectactin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005522
ISS
IEA
Genome Projectprofilin binding
GO:0017124
ISS
IEA
Genome ProjectSH3 domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISS
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005925
ISS
IEA
Genome Projectfocal adhesion
GO:0016020
IDA
Genome Projectmembrane
GO:0030027
ISS
IEA
Genome Projectlamellipodium
GO:0042995
IEA
Genome Projectcell projection

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000697WH1/EVH1 domain
IPR011993PH domain-like
IPR014885VASP tetramerisation
IPR017354Vasodilator-stimulated phosphoprotein

No MapMan annotations defined for this gene.