Gene: ENSG00000196338 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000196338
Transcript Identifier
ENST00000358741
Gene Type
Coding gene
Location
X : 71147750-71170097 : positive

Family Information

Homologous gene family
HOM03P000191
(174 genes in 16 species)
specific family
Orthologous gene family
ORTHO03P008154
(10 genes in 4 species)
specific family

Descriptions

gene_descr
neuroligin 3

Identifiers

Type Value
pidENSP00000351591
HGNC14289
UniprotQ9NZ94
UniprotX5DNV3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002087
ISS
IEA
Genome Projectregulation of respiratory gaseous exchange by neurological system process
GO:0006898
ISS
Genome Projectreceptor-mediated endocytosis
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007158
ISS, IBA
Genome Projectneuron cell-cell adhesion
GO:0007416
ISS
Genome Projectsynapse assembly
GO:0007612
IMP
Genome Projectlearning
GO:0008542
IEA
Genome Projectvisual learning
GO:0030534
IMP
Genome Projectadult behavior
GO:0035176
IMP
Genome Projectsocial behavior
GO:0048488
IBA
Genome Projectsynaptic vesicle endocytosis
GO:0048675
ISS
Genome Projectaxon extension
GO:0048709
IEA
Genome Projectoligodendrocyte differentiation
GO:0050804
ISS, IBA
IEA
Genome Projectmodulation of synaptic transmission
GO:0050808
IMP
IEA
Genome Projectsynapse organization
GO:0051965
ISS
Genome Projectpositive regulation of synapse assembly
GO:0051966
IEA
Genome Projectregulation of synaptic transmission, glutamatergic
GO:0051968
ISS
IEA
Genome Projectpositive regulation of synaptic transmission, glutamatergic
GO:0060024
ISS
Genome Projectrhythmic synaptic transmission
GO:0060079
IEA
Genome Projectexcitatory postsynaptic potential
GO:0060080
ISS
IEA
Genome Projectinhibitory postsynaptic potential
GO:0060291
IEA
Genome Projectlong-term synaptic potentiation
GO:0060999
IEA
Genome Projectpositive regulation of dendritic spine development
GO:0061001
IEA
Genome Projectregulation of dendritic spine morphogenesis
GO:0061002
IEA
Genome Projectnegative regulation of dendritic spine morphogenesis
GO:0071625
IMP
Genome Projectvocalization behavior
GO:0090394
IEA
Genome Projectnegative regulation of excitatory postsynaptic potential
GO:0097104
ISS, IBA
IEA
Genome Projectpostsynaptic membrane assembly
GO:0097105
ISS, IBA
Genome Projectpresynaptic membrane assembly
GO:0097151
IEA
Genome Projectpositive regulation of inhibitory postsynaptic potential
GO:1900271
IEA
Genome Projectregulation of long-term synaptic potentiation
GO:1902474
IEA
Genome Projectpositive regulation of protein localization to synapse
GO:2000310
IEA
Genome Projectregulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000311
IEA
Genome Projectregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000331
IEA
Genome Projectregulation of terminal button organization
GO:2000463
ISS
IEA
Genome Projectpositive regulation of excitatory postsynaptic potential
GO:2000809
IEA
Genome Projectpositive regulation of synaptic vesicle clustering
GO:2000969
ISS
IEA
Genome Projectpositive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0006581
IBA
Genome Projectacetylcholine catabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004872
ISS, IBA
Genome Projectreceptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0042043
ISS, IBA
IEA
Genome Projectneurexin family protein binding
GO:0050839
ISS
Genome Projectcell adhesion molecule binding
GO:0097110
IPI
Genome Projectscaffold protein binding
GO:0004104
IBA
Genome Projectcholinesterase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005887
ISS, IBA
IEA
Genome Projectintegral component of plasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030139
ISS
Genome Projectendocytic vesicle
GO:0030425
IEA
Genome Projectdendrite
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0045202
ISS
IEA
Genome Projectsynapse
GO:0060076
IDA
IEA
Genome Projectexcitatory synapse
GO:0060077
IEA
Genome Projectinhibitory synapse
GO:0005615
IBA
Genome Projectextracellular space

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000460Neuroligin
IPR002018Carboxylesterase, type B
IPR019819Carboxylesterase type B, conserved site
IPR029058Alpha/Beta hydrolase fold

No MapMan annotations defined for this gene.