Gene: ENSG00000196277 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000196277
Transcript Identifier
ENST00000486284
Gene Type
Coding gene
Location
3 : 6861389-7686427 : positive

Family Information

Homologous gene family
HOM03P000228
(156 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P004612
(18 genes in 4 species)
specific family

Descriptions

gene_descr
glutamate receptor, metabotropic 7

Identifiers

Type Value
pidENSP00000417536
HGNC4599
UniprotQ14831

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001661
IEA
Genome Projectconditioned taste aversion
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007194
IDA
Genome Projectnegative regulation of adenylate cyclase activity
GO:0007196
IDA
Genome Projectadenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007268
IDA
Genome Projectsynaptic transmission
GO:0007605
IMP
Genome Projectsensory perception of sound
GO:0007608
IEA
Genome Projectsensory perception of smell
GO:0007613
IEA
Genome Projectmemory
GO:0007614
IEA
Genome Projectshort-term memory
GO:0008306
IEA
Genome Projectassociative learning
GO:0014050
ISS
Genome Projectnegative regulation of glutamate secretion
GO:0019226
IEA
Genome Projecttransmission of nerve impulse
GO:0030534
IEA
Genome Projectadult behavior
GO:0030818
IDA
Genome Projectnegative regulation of cAMP biosynthetic process
GO:0031279
IDA
Genome Projectregulation of cyclase activity
GO:0033555
IEA
Genome Projectmulticellular organismal response to stress
GO:0050877
IEA
Genome Projectneurological system process
GO:0050896
IEA
Genome Projectresponse to stimulus
GO:0051966
IBA
Genome Projectregulation of synaptic transmission, glutamatergic
GO:0070588
IEA
Genome Projectcalcium ion transmembrane transport
GO:0001662
IMP
Genome Projectbehavioral fear response

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001642
IDA
Genome Projectgroup III metabotropic glutamate receptor activity
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0005245
IEA
Genome Projectvoltage-gated calcium channel activity
GO:0005246
IBA
IEA
Genome Projectcalcium channel regulator activity
GO:0005509
IDA
Genome Projectcalcium ion binding
GO:0008066
IDA
Genome Projectglutamate receptor activity
GO:0010855
IDA
Genome Projectadenylate cyclase inhibitor activity
GO:0016595
IDA
Genome Projectglutamate binding
GO:0030165
NAS
Genome ProjectPDZ domain binding
GO:0070905
IDA
Genome Projectserine binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
IBA
NAS
Genome Projectintegral component of plasma membrane
GO:0005938
IDA
Genome Projectcell cortex
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IDA
IEA
Genome Projectintegral component of membrane
GO:0030424
ISS
Genome Projectaxon
GO:0030425
IDA
Genome Projectdendrite
GO:0032279
ISS
Genome Projectasymmetric synapse
GO:0042734
IBA
IEA
Genome Projectpresynaptic membrane
GO:0043198
ISS
Genome Projectdendritic shaft
GO:0043235
IDA
Genome Projectreceptor complex
GO:0045211
ISS
Genome Projectpostsynaptic membrane
GO:0048786
ISS
Genome Projectpresynaptic active zone

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000162GPCR, family 3, metabotropic glutamate receptor
IPR000337GPCR, family 3
IPR001828Receptor, ligand binding region
IPR001883GPCR, family 3, metabotropic glutamate receptor 7
IPR011500GPCR, family 3, nine cysteines domain
IPR017978GPCR family 3, C-terminal
IPR017979GPCR, family 3, conserved site
IPR028082Periplasmic binding protein-like I

No MapMan annotations defined for this gene.