Gene: ENSG00000196139 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000196139
Transcript Identifier
ENST00000380554
Gene Type
Coding gene
Location
10 : 5094445-5107503 : positive

Family Information

Homologous gene family
HOM03P000087
(311 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P017638
(5 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
aldo-keto reductase family 1, member C3

Identifiers

Type Value
pidENSP00000369927
HGNC386
UniprotP42330

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000060
IDA
Genome Projectprotein import into nucleus, translocation
GO:0001523
TAS
Genome Projectretinoid metabolic process
GO:0006693
IEP
TAS
Genome Projectprostaglandin metabolic process
GO:0007186
IDA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007584
IEP
Genome Projectresponse to nutrient
GO:0007603
TAS
Genome Projectphototransduction, visible light
GO:0008202
IEP
Genome Projectsteroid metabolic process
GO:0008284
IDA, IMP
Genome Projectpositive regulation of cell proliferation
GO:0008584
IEP
Genome Projectmale gonad development
GO:0009267
IEP
Genome Projectcellular response to starvation
GO:0010942
IDA
Genome Projectpositive regulation of cell death
GO:0016488
IDA
Genome Projectfarnesol catabolic process
GO:0019369
TAS
Genome Projectarachidonic acid metabolic process
GO:0019371
TAS
Genome Projectcyclooxygenase pathway
GO:0030216
IEP
Genome Projectkeratinocyte differentiation
GO:0034614
IDA
Genome Projectcellular response to reactive oxygen species
GO:0042448
IDA
Genome Projectprogesterone metabolic process
GO:0042574
IDA
Genome Projectretinal metabolic process
GO:0044259
IEP
Genome Projectmulticellular organismal macromolecule metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0044597
IMP
Genome Projectdaunorubicin metabolic process
GO:0044598
IMP
Genome Projectdoxorubicin metabolic process
GO:0048385
IDA
Genome Projectregulation of retinoic acid receptor signaling pathway
GO:0051897
IDA
Genome Projectpositive regulation of protein kinase B signaling
GO:0055114
IDA
TAS, IEA
Genome Projectoxidation-reduction process
GO:0061370
IMP
Genome Projecttestosterone biosynthetic process
GO:0070293
NAS
Genome Projectrenal absorption
GO:0071276
IDA
Genome Projectcellular response to cadmium ion
GO:0071277
IDA
Genome Projectcellular response to calcium ion
GO:0071379
IDA
Genome Projectcellular response to prostaglandin stimulus
GO:0071384
IDA
Genome Projectcellular response to corticosteroid stimulus
GO:0071395
IDA
Genome Projectcellular response to jasmonic acid stimulus
GO:0071799
IDA
Genome Projectcellular response to prostaglandin D stimulus
GO:1900053
IDA
Genome Projectnegative regulation of retinoic acid biosynthetic process
GO:2000224
IMP
Genome Projectregulation of testosterone biosynthetic process
GO:2000353
IDA
Genome Projectpositive regulation of endothelial cell apoptotic process
GO:2000379
IDA
Genome Projectpositive regulation of reactive oxygen species metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001758
IDA
Genome Projectretinal dehydrogenase activity
GO:0004032
IDA
Genome Projectalditol:NADP+ 1-oxidoreductase activity
GO:0004033
TAS
Genome Projectaldo-keto reductase (NADP) activity
GO:0004745
IDA
Genome Projectretinol dehydrogenase activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016655
IDA
Genome Projectoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018636
IDA
Genome Projectphenanthrene 9,10-monooxygenase activity
GO:0035410
IDA
Genome Projectdihydrotestosterone 17-beta-dehydrogenase activity
GO:0036131
IEA
Genome Projectprostaglandin D2 11-ketoreductase activity
GO:0045550
IDA
Genome Projectgeranylgeranyl reductase activity
GO:0045703
IDA
Genome Projectketoreductase activity
GO:0047017
IEA
Genome Projectprostaglandin-F synthase activity
GO:0047020
IDA
Genome Project15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
GO:0047023
IDA
Genome Projectandrosterone dehydrogenase activity
GO:0047035
IEA
Genome Projecttestosterone dehydrogenase (NAD+) activity
GO:0047045
IEA
Genome Projecttestosterone 17-beta-dehydrogenase (NADP+) activity
GO:0047086
IDA
Genome Projectketosteroid monooxygenase activity
GO:0047115
IEA
Genome Projecttrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
GO:0047718
IEA
Genome Projectindanol dehydrogenase activity
GO:0047787
IDA
Genome Projectdelta4-3-oxosteroid 5beta-reductase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IDA
Genome Projectintracellular
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001395Aldo/keto reductase/potassium channel subunit beta
IPR018170Aldo/keto reductase, conserved site
IPR020471Aldo/keto reductase
IPR023210NADP-dependent oxidoreductase domain

No MapMan annotations defined for this gene.