Gene: ENSG00000188778 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000188778
Transcript Identifier
ENST00000614635
Gene Type
Coding gene
Location
8 : 37964218-37966469 : negative

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P073108
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
adrenoceptor beta 3

Identifiers

Type Value
pidENSP00000480325
HGNC288
UniprotP13945
UniprotA8KAG8

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002024
IEA
Genome Projectdiet induced thermogenesis
GO:0002025
IBA
IEA
Genome Projectvasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007189
IEA
Genome Projectadenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007568
IEA
Genome Projectaging
GO:0009409
IEA
Genome Projectresponse to cold
GO:0031649
IEA
Genome Projectheat generation
GO:0040015
IEA
Genome Projectnegative regulation of multicellular organism growth
GO:0042755
IEA
Genome Projecteating behavior
GO:0046677
IEA
Genome Projectresponse to antibiotic
GO:0050873
IEA
Genome Projectbrown fat cell differentiation
GO:0071875
IEA
Genome Projectadrenergic receptor signaling pathway
GO:0001659
IBA
Genome Projecttemperature homeostasis
GO:0005975
TAS
Genome Projectcarbohydrate metabolic process
GO:0006091
TAS
Genome Projectgeneration of precursor metabolites and energy
GO:0006112
TAS
Genome Projectenergy reserve metabolic process
GO:0007187
TAS
Genome ProjectG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007188
TAS
Genome Projectadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007190
IDA
Genome Projectactivation of adenylate cyclase activity
GO:0007267
IBA
Genome Projectcell-cell signaling
GO:0043410
IDA
Genome Projectpositive regulation of MAPK cascade
GO:0071880
IBA
Genome Projectadenylate cyclase-activating adrenergic receptor signaling pathway
GO:0002032
IDA
Genome Projectdesensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0006898
IDA
Genome Projectreceptor-mediated endocytosis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004935
IEA
Genome Projectadrenergic receptor activity
GO:0004939
IDA
IEA
Genome Projectbeta-adrenergic receptor activity
GO:0031699
IEA
Genome Projectbeta-3 adrenergic receptor binding
GO:0051379
IBA
IEA
Genome Projectepinephrine binding
GO:0051380
IDA
IEA
Genome Projectnorepinephrine binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0015052
IMP
Genome Projectbeta3-adrenergic receptor activity
GO:0042803
IDA
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0043235
IDA
Genome Projectreceptor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000681Beta 3 adrenoceptor
IPR002233Adrenoceptor family
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.