Gene: ENSG00000187554 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000187554
Transcript Identifier
ENST00000366881
Gene Type
Coding gene
Location
1 : 223110455-223113031 : negative

Family Information

Homologous gene family
HOM03P004593
(20 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P073936
(2 genes in 2 species)
specific family

Descriptions

gene_descr
toll-like receptor 5

Identifiers

Type Value
pidENSP00000355846
HGNC11851
UniprotO60602

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001819
IEA
Genome Projectpositive regulation of cytokine production
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002376
IEA
Genome Projectimmune system process
GO:0002755
TAS, IEA
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0008584
IEA
Genome Projectmale gonad development
GO:0032757
IDA
Genome Projectpositive regulation of interleukin-8 production
GO:0034123
IDA
Genome Projectpositive regulation of toll-like receptor signaling pathway
GO:0034146
TAS, IEA
Genome Projecttoll-like receptor 5 signaling pathway
GO:0034166
TAS
Genome Projecttoll-like receptor 10 signaling pathway
GO:0042742
IEA
Genome Projectdefense response to bacterium
GO:0045087
TAS, IEA
Genome Projectinnate immune response
GO:0045429
IEA
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0050707
IEA
Genome Projectregulation of cytokine secretion
GO:0071222
IEA
Genome Projectcellular response to lipopolysaccharide
GO:0071260
IEP
Genome Projectcellular response to mechanical stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004888
IEA
Genome Projecttransmembrane signaling receptor activity
GO:0005149
IPI
Genome Projectinterleukin-1 receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000157Toll/interleukin-1 receptor homology (TIR) domain
IPR000483Cysteine-rich flanking region, C-terminal
IPR001611Leucine-rich repeat
IPR003591Leucine-rich repeat, typical subtype
IPR027176Toll-like receptor 5

No MapMan annotations defined for this gene.