Gene: ENSG00000187446 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000187446
Transcript Identifier
ENST00000334660
Gene Type
Coding gene
Location
15 : 41231383-41279389 : positive

Family Information

Homologous gene family
HOM03P002028
(41 genes in 28 species)
specific family
Orthologous gene family
ORTHO03P015271
(6 genes in 5 species)
specific family

Descriptions

gene_descr
calcineurin-like EF-hand protein 1

Identifiers

Type Value
pidENSP00000335632
HGNC17433
UniprotQ99653
UniprotA0A024R9M9

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001578
ISS
IEA
Genome Projectmicrotubule bundle formation
GO:0001933
ISS
IEA
Genome Projectnegative regulation of protein phosphorylation
GO:0006469
ISS
IEA
Genome Projectnegative regulation of protein kinase activity
GO:0006611
ISS
IEA
Genome Projectprotein export from nucleus
GO:0017156
IEA
Genome Projectcalcium ion-dependent exocytosis
GO:0022406
ISS
IEA
Genome Projectmembrane docking
GO:0031122
ISS
IEA
Genome Projectcytoplasmic microtubule organization
GO:0031397
ISS
IEA
Genome Projectnegative regulation of protein ubiquitination
GO:0031953
ISS
IEA
Genome Projectnegative regulation of protein autophosphorylation
GO:0051222
ISS
IEA
Genome Projectpositive regulation of protein transport
GO:0051259
IEA
Genome Projectprotein oligomerization
GO:0060050
ISS
IEA
Genome Projectpositive regulation of protein glycosylation
GO:0061024
ISS
IEA
Genome Projectmembrane organization
GO:0061025
ISS
IEA
Genome Projectmembrane fusion
GO:0005975
TAS
Genome Projectcarbohydrate metabolic process
GO:0006810
IEA
Genome Projecttransport
GO:0006813
TAS
Genome Projectpotassium ion transport
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0010923
IDA
Genome Projectnegative regulation of phosphatase activity
GO:0015031
IEA
Genome Projectprotein transport
GO:0030203
TAS
Genome Projectglycosaminoglycan metabolic process
GO:0030212
TAS
Genome Projecthyaluronan metabolic process
GO:0030214
TAS
Genome Projecthyaluronan catabolic process
GO:0032088
IDA
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0032417
IDA
ISS
Genome Projectpositive regulation of sodium:proton antiporter activity
GO:0042308
IDA
Genome Projectnegative regulation of protein import into nucleus
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0050821
ISS
Genome Projectprotein stabilization
GO:0051453
IDA
Genome Projectregulation of intracellular pH
GO:0070885
IDA
Genome Projectnegative regulation of calcineurin-NFAT signaling cascade
GO:0071468
ISS
Genome Projectcellular response to acidic pH
GO:0090314
ISS
Genome Projectpositive regulation of protein targeting to membrane
GO:1901214
IMP
Genome Projectregulation of neuron death
GO:1904030
IEA
Genome Projectnegative regulation of cyclin-dependent protein kinase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005215
ISS
IEA
Genome Projecttransporter activity
GO:0005509
IDA
IEA
Genome Projectcalcium ion binding
GO:0008017
ISS
IEA
Genome Projectmicrotubule binding
GO:0019900
ISS
IEA
Genome Projectkinase binding
GO:0004860
IEA
Genome Projectprotein kinase inhibitor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0015459
TAS
Genome Projectpotassium channel regulator activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0048306
IDA
Genome Projectcalcium-dependent protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
ISS
IEA
Genome ProjectGolgi membrane
GO:0005634
ISS
IEA
Genome Projectnucleus
GO:0005737
ISS
IEA
Genome Projectcytoplasm
GO:0005783
ISS
IEA
Genome Projectendoplasmic reticulum
GO:0005829
IEA
Genome Projectcytosol
GO:0015630
ISS
IEA
Genome Projectmicrotubule cytoskeleton
GO:0030133
ISS
IEA
Genome Projecttransport vesicle
GO:0005793
IEA
Genome Projectendoplasmic reticulum-Golgi intermediate compartment
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0016020
IEA
Genome Projectmembrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002048EF-hand domain
IPR011992EF-hand domain pair

No MapMan annotations defined for this gene.