Gene: ENSG00000186868 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000186868
Transcript Identifier
ENST00000415613
Gene Type
Coding gene
Location
17 : 45962338-46024171 : positive

Family Information

Homologous gene family
HOM03P010747
(8 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P032909
(3 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
microtubule-associated protein tau

Identifiers

Type Value
pidENSP00000410838
HGNC6893
UniprotP10636

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000226
IDA
Genome Projectmicrotubule cytoskeleton organization
GO:0001764
IEA
Genome Projectneuron migration
GO:0006915
TAS, IEA
Genome Projectapoptotic process
GO:0006921
TAS
Genome Projectcellular component disassembly involved in execution phase of apoptosis
GO:0007409
IEA
Genome Projectaxonogenesis
GO:0007420
IEA
Genome Projectbrain development
GO:0007565
IEA
Genome Projectfemale pregnancy
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0007628
IEA
Genome Projectadult walking behavior
GO:0008088
IEA
Genome Projectaxon cargo transport
GO:0008631
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to oxidative stress
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010506
IGI
Genome Projectregulation of autophagy
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0031113
NAS
Genome Projectregulation of microtubule polymerization
GO:0031116
IDA
Genome Projectpositive regulation of microtubule polymerization
GO:0032387
IEA
Genome Projectnegative regulation of intracellular transport
GO:0045773
IDA
Genome Projectpositive regulation of axon extension
GO:0047497
IEA
Genome Projectmitochondrion transport along microtubule
GO:0048675
IEA
Genome Projectaxon extension
GO:0048699
NAS
Genome Projectgeneration of neurons
GO:0060632
IEA
Genome Projectregulation of microtubule-based movement

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005200
TAS
Genome Projectstructural constituent of cytoskeleton
GO:0005515
IPI
Genome Projectprotein binding
GO:0008017
IDA
IEA
Genome Projectmicrotubule binding
GO:0015631
IEA
Genome Projecttubulin binding
GO:0017124
IPI
Genome ProjectSH3 domain binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0034185
IPI
Genome Projectapolipoprotein binding
GO:0051721
IEA
Genome Projectprotein phosphatase 2A binding
GO:0071813
IPI
Genome Projectlipoprotein particle binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005874
IEA
Genome Projectmicrotubule
GO:0005875
TAS
Genome Projectmicrotubule associated complex
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0005930
IEA
Genome Projectaxoneme
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0015630
IEA
Genome Projectmicrotubule cytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0030424
IDA
IEA
Genome Projectaxon
GO:0030426
IDA
Genome Projectgrowth cone
GO:0034399
IDA
Genome Projectnuclear periphery
GO:0036464
IDA
Genome Projectcytoplasmic ribonucleoprotein granule
GO:0042995
IEA
Genome Projectcell projection
GO:0043005
IEA
Genome Projectneuron projection
GO:0045298
IDA
Genome Projecttubulin complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001084Microtubule associated protein, tubulin-binding repeat
IPR002955Microtubule-associated protein Tau
IPR027324Microtubule associated protein MAP2/MAP4/Tau

No MapMan annotations defined for this gene.