Gene: ENSG00000186038 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000186038
Transcript Identifier
ENST00000440596
Gene Type
Coding gene
Location
3 : 184100373-184106693 : positive

Family Information

Homologous gene family
HOM03P000517
(94 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P032908
(3 genes in 1 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
5-hydroxytryptamine (serotonin) receptor 3E, ionotropic

Identifiers

Type Value
pidENSP00000406050
HGNC24005
UniprotA5X5Y0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0007210
IDA
Genome Projectserotonin receptor signaling pathway
GO:0034220
TAS
Genome Projection transmembrane transport
GO:0042391
IBA
Genome Projectregulation of membrane potential
GO:0050877
IBA
Genome Projectneurological system process
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0098655
IBA
Genome Projectcation transmembrane transport
GO:0007271
IBA
Genome Projectsynaptic transmission, cholinergic
GO:0007274
IBA
Genome Projectneuromuscular synaptic transmission
GO:0035094
IBA
Genome Projectresponse to nicotine

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004993
IDA
Genome Projectserotonin receptor activity
GO:0005230
IEA
Genome Projectextracellular ligand-gated ion channel activity
GO:0005232
IBA
Genome Projectserotonin-activated cation-selective channel activity
GO:0004889
IBA
Genome Projectacetylcholine-activated cation-selective channel activity
GO:0015464
IBA
Genome Projectacetylcholine receptor activity
GO:0042166
IBA
Genome Projectacetylcholine binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0043005
IBA
Genome Projectneuron projection
GO:0045202
IBA
Genome Projectsynapse
GO:0005892
IBA
Genome Projectacetylcholine-gated channel complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR006029Neurotransmitter-gated ion-channel transmembrane domain
IPR006201Neurotransmitter-gated ion-channel
IPR006202Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000Neurotransmitter-gated ion-channel, conserved site
IPR027361Nicotinic acetylcholine-gated receptor, transmembrane domain

No MapMan annotations defined for this gene.