Gene: ENSG00000185811 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000185811
Transcript Identifier
ENST00000331340
Gene Type
Coding gene
Location
7 : 50319062-50400627 : positive

Family Information

Homologous gene family
HOM03P000007
(1601 genes in 28 species)
specific family
Orthologous gene family
ORTHO03P076537
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
IKAROS family zinc finger 1 (Ikaros)

Identifiers

Type Value
pidENSP00000331614
HGNC13176
UniprotQ13422

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001779
IEA
Genome Projectnatural killer cell differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0007049
IEA
Genome Projectcell cycle
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007498
TAS
Genome Projectmesoderm development
GO:0016568
IEA
Genome Projectchromatin modification
GO:0030097
IEA
Genome Projecthemopoiesis
GO:0030098
IMP
Genome Projectlymphocyte differentiation
GO:0030183
IEA
Genome ProjectB cell differentiation
GO:0030217
IEA
Genome ProjectT cell differentiation
GO:0030218
IMP
Genome Projecterythrocyte differentiation
GO:0030900
IEA
Genome Projectforebrain development
GO:0040018
IEA
Genome Projectpositive regulation of multicellular organism growth
GO:0045579
IEA
Genome Projectpositive regulation of B cell differentiation
GO:0045660
IEA
Genome Projectpositive regulation of neutrophil differentiation
GO:0045892
ISS
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048535
IEA
Genome Projectlymph node development
GO:0048538
IEA
Genome Projectthymus development
GO:0048541
IEA
Genome ProjectPeyer's patch development
GO:0048732
IEA
Genome Projectgland development
GO:0051138
IEA
Genome Projectpositive regulation of NK T cell differentiation
GO:0060041
IEA
Genome Projectretina development in camera-type eye

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
IDA
TAS, IEA
Genome ProjectDNA binding
GO:0003700
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005721
IEA
Genome Projectpericentric heterochromatin
GO:0005737
IEA
Genome Projectcytoplasm
GO:0043234
IDA
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007087Zinc finger, C2H2
IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
IPR015880Zinc finger, C2H2-like

No MapMan annotations defined for this gene.