Gene: ENSG00000185624 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000185624
Transcript Identifier
ENST00000331483
Gene Type
Coding gene
Location
17 : 81844012-81860471 : negative

Family Information

Homologous gene family
HOM03P000075
(354 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P001412
(38 genes in 29 species)
specific family

Descriptions

gene_descr
prolyl 4-hydroxylase, beta polypeptide

Identifiers

Type Value
pidENSP00000327801
HGNC8548
UniprotP07237
UniprotA0A024R8S5

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006457
IBA
IEA
Genome Projectprotein folding
GO:0008152
IEA
Genome Projectmetabolic process
GO:0045454
IEA
Genome Projectcell redox homeostasis
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0000302
TAS
Genome Projectresponse to reactive oxygen species
GO:0006508
TAS
Genome Projectproteolysis
GO:0018401
IDA
Genome Projectpeptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0030198
TAS
Genome Projectextracellular matrix organization
GO:0034976
IMP
Genome Projectresponse to endoplasmic reticulum stress
GO:0042157
TAS
Genome Projectlipoprotein metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0046598
IMP
Genome Projectpositive regulation of viral entry into host cell
GO:0071456
IMP
Genome Projectcellular response to hypoxia
GO:1902175
IMP
Genome Projectregulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003756
IDA
TAS, IEA
Genome Projectprotein disulfide isomerase activity
GO:0016853
IEA
Genome Projectisomerase activity
GO:0019899
IEA
Genome Projectenzyme binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity
GO:0051213
IEA
Genome Projectdioxygenase activity
GO:0004175
TAS
Genome Projectendopeptidase activity
GO:0004656
IDA
TAS
Genome Projectprocollagen-proline 4-dioxygenase activity
GO:0005178
IPI
Genome Projectintegrin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IDA
TAS, IEA
Genome Projectendoplasmic reticulum
GO:0034663
IEA
Genome Projectendoplasmic reticulum chaperone complex
GO:0005576
NAS
Genome Projectextracellular region
GO:0005788
TAS, IEA
Genome Projectendoplasmic reticulum lumen
GO:0005793
IDA
Genome Projectendoplasmic reticulum-Golgi intermediate compartment
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016222
IDA
Genome Projectprocollagen-proline 4-dioxygenase complex
GO:0042470
IEA
Genome Projectmelanosome
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR005788Disulphide isomerase
IPR005792Protein disulphide isomerase
IPR012336Thioredoxin-like fold
IPR013766Thioredoxin domain
IPR017937Thioredoxin, conserved site

No MapMan annotations defined for this gene.