Gene: ENSG00000185104 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000185104
Transcript Identifier
ENST00000396153
Gene Type
Coding gene
Location
1 : 50441440-50959811 : negative

Family Information

Homologous gene family
HOM03P001604
(48 genes in 36 species)
specific family
Orthologous gene family
ORTHO03P027051
(4 genes in 4 species)
specific family

Descriptions

gene_descr
Fas (TNFRSF6) associated factor 1

Identifiers

Type Value
pidENSP00000379457
HGNC3578
UniprotQ9UNN5

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007253
IMP
Genome Projectcytoplasmic sequestering of NF-kappaB
GO:0008219
IMP
Genome Projectcell death
GO:0010942
IDA
Genome Projectpositive regulation of cell death
GO:0030155
IEA
Genome Projectregulation of cell adhesion
GO:0031334
IMP
Genome Projectpositive regulation of protein complex assembly
GO:0042176
IMP
Genome Projectregulation of protein catabolic process
GO:0043065
NAS
Genome Projectpositive regulation of apoptotic process
GO:0043161
NAS
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045859
NAS
Genome Projectregulation of protein kinase activity
GO:1902043
IEA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0019887
NAS
Genome Projectprotein kinase regulator activity
GO:0019901
IDA
Genome Projectprotein kinase binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0031072
IDA
Genome Projectheat shock protein binding
GO:0031625
IDA
Genome Projectubiquitin protein ligase binding
GO:0043130
IDA
Genome Projectubiquitin binding
GO:0051059
IPI
Genome ProjectNF-kappaB binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005635
IEA
Genome Projectnuclear envelope
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IDA
Genome Projectcytosol
GO:0031265
NAS
Genome ProjectCD95 death-inducing signaling complex
GO:0034098
IDA
Genome ProjectVCP-NPL4-UFD1 AAA ATPase complex
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001012UBX domain
IPR006577UAS
IPR012336Thioredoxin-like fold
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.