Gene: ENSG00000185043 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000185043
Transcript Identifier
ENST00000612800
Gene Type
Coding gene
Location
15 : 90230484-90233885 : negative

Family Information

Homologous gene family
HOM03P000598
(86 genes in 30 species)
specific family

Descriptions

gene_descr
calcium and integrin binding 1 (calmyrin)

Identifiers

Type Value
pidENSP00000479860
HGNC16920
UniprotQ99828

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001933
ISS
IEA
Genome Projectnegative regulation of protein phosphorylation
GO:0001934
ISS
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0001954
ISS
IEA
Genome Projectpositive regulation of cell-matrix adhesion
GO:0002931
ISS
IEA
Genome Projectresponse to ischemia
GO:0006302
TAS
Genome Projectdouble-strand break repair
GO:0006915
IMP
IEA
Genome Projectapoptotic process
GO:0006974
IDA
Genome Projectcellular response to DNA damage stimulus
GO:0007026
IDA
Genome Projectnegative regulation of microtubule depolymerization
GO:0007049
IEA
Genome Projectcell cycle
GO:0007113
IDA
Genome Projectendomitotic cell cycle
GO:0007155
TAS, IEA
Genome Projectcell adhesion
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0007286
ISS
IEA
Genome Projectspermatid development
GO:0008284
ISS
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0010977
IDA
Genome Projectnegative regulation of neuron projection development
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030220
ISS
IEA
Genome Projectplatelet formation
GO:0030307
ISS
IEA
Genome Projectpositive regulation of cell growth
GO:0030335
ISS
IEA
Genome Projectpositive regulation of cell migration
GO:0031122
IMP
Genome Projectcytoplasmic microtubule organization
GO:0033630
IDA
Genome Projectpositive regulation of cell adhesion mediated by integrin
GO:0038163
ISS
IEA
Genome Projectthrombopoietin-mediated signaling pathway
GO:0042127
IMP
Genome Projectregulation of cell proliferation
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0045653
ISS
IEA
Genome Projectnegative regulation of megakaryocyte differentiation
GO:0048554
ISS
IEA
Genome Projectpositive regulation of metalloenzyme activity
GO:0051092
IMP
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051301
IEA
Genome Projectcell division
GO:0051302
IMP
Genome Projectregulation of cell division
GO:0051898
ISS
IEA
Genome Projectnegative regulation of protein kinase B signaling
GO:0070374
ISS
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070886
IDA
IEA
Genome Projectpositive regulation of calcineurin-NFAT signaling cascade
GO:0071356
IMP
Genome Projectcellular response to tumor necrosis factor
GO:0071363
ISS
IEA
Genome Projectcellular response to growth factor stimulus
GO:0071901
IDA
Genome Projectnegative regulation of protein serine/threonine kinase activity
GO:0071902
ISS
IEA
Genome Projectpositive regulation of protein serine/threonine kinase activity
GO:0090004
IGI
Genome Projectpositive regulation of establishment of protein localization to plasma membrane
GO:0090050
ISS
IEA
Genome Projectpositive regulation of cell migration involved in sprouting angiogenesis
GO:0090314
IMP
Genome Projectpositive regulation of protein targeting to membrane
GO:0097191
TAS
Genome Projectextrinsic apoptotic signaling pathway
GO:1900026
IDA
Genome Projectpositive regulation of substrate adhesion-dependent cell spreading
GO:1904030
IMP
Genome Projectnegative regulation of cyclin-dependent protein kinase activity
GO:1990090
IDA
Genome Projectcellular response to nerve growth factor stimulus
GO:2000256
ISS
IEA
Genome Projectpositive regulation of male germ cell proliferation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005509
IMP
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008427
IMP
Genome Projectcalcium-dependent protein kinase inhibitor activity
GO:0017016
IPI
Genome ProjectRas GTPase binding
GO:0030291
IDA
Genome Projectprotein serine/threonine kinase inhibitor activity
GO:0043495
IGI
Genome Projectprotein anchor
GO:0044325
IEA
Genome Projection channel binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA, IMP
Genome Projectnucleoplasm
GO:0005737
IDA, IMP
IEA
Genome Projectcytoplasm
GO:0005783
IMP
Genome Projectendoplasmic reticulum
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005813
IDA
Genome Projectcentrosome
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016324
IEA
Genome Projectapical plasma membrane
GO:0030027
IDA
IEA
Genome Projectlamellipodium
GO:0030426
IDA
IEA
Genome Projectgrowth cone
GO:0031982
IDA
Genome Projectvesicle
GO:0032433
IDA
IEA
Genome Projectfilopodium tip
GO:0032587
IEA
Genome Projectruffle membrane
GO:0042383
IDA
IEA
Genome Projectsarcolemma
GO:0042995
IEA
Genome Projectcell projection
GO:0043005
IDA
Genome Projectneuron projection
GO:0043025
IDA
Genome Projectneuronal cell body
GO:0048471
IDA
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0071944
IDA
Genome Projectcell periphery

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002048EF-hand domain
IPR011992EF-hand domain pair
IPR018247EF-Hand 1, calcium-binding site

No MapMan annotations defined for this gene.