Gene: ENSG00000184922 (Homo sapiens)

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Gene Identifier
ENSG00000184922
Transcript Identifier
ENST00000331495
Gene Type
Coding gene
Location
17 : 45222125-45246596 : positive

Family Information

Homologous gene family
HOM03P000137
(217 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P003527
(23 genes in 20 species)
specific family

Descriptions

gene_descr
formin-like 1

Identifiers

Type Value
pidENSP00000329219
HGNC1212
UniprotO95466

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006929
IEA
Genome Projectsubstrate-dependent cell migration
GO:0007010
IEA
Genome Projectcytoskeleton organization
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0008360
IMP
IEA
Genome Projectregulation of cell shape
GO:0009987
IEA
Genome Projectcellular process
GO:0016043
IEA
Genome Projectcellular component organization
GO:0030036
IEA
Genome Projectactin cytoskeleton organization
GO:0030866
IMP
Genome Projectcortical actin cytoskeleton organization
GO:0051014
ISS
IEA
Genome Projectactin filament severing

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003674
ND
Genome Projectmolecular_function
GO:0003779
IEA
Genome Projectactin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005522
IEA
Genome Projectprofilin binding
GO:0017048
IEA
Genome ProjectRho GTPase binding
GO:0032794
IDA
IEA
Genome ProjectGTPase activating protein binding
GO:0048365
ISS
IEA
Genome ProjectRac GTPase binding
GO:0051015
ISS
IEA
Genome Projectactin filament binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
ISS
TAS, IEA
Genome Projectcytosol
GO:0005886
ISS
IEA
Genome Projectplasma membrane
GO:0005938
IEA
Genome Projectcell cortex
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0032059
IEA
Genome Projectbleb
GO:0042995
IEA
Genome Projectcell projection
GO:0045335
ISS
IEA
Genome Projectphagocytic vesicle
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR010472Formin, FH3 domain
IPR010473Formin, GTPase-binding domain
IPR014767Diaphanous autoregulatory (DAD) domain
IPR014768Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
IPR015425Formin, FH2 domain
IPR016024Armadillo-type fold
IPR027657Formin-like protein 1

No MapMan annotations defined for this gene.