Gene: ENSG00000184845 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000184845
Transcript Identifier
ENST00000393752
Gene Type
Coding gene
Location
5 : 175441759-175443099 : negative

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P074916
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
dopamine receptor D1

Identifiers

Type Value
pidENSP00000377353
HGNC3020
UniprotP21728

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001659
IEA
Genome Projecttemperature homeostasis
GO:0001661
IEA
Genome Projectconditioned taste aversion
GO:0001662
IEA
Genome Projectbehavioral fear response
GO:0001963
IBA
IEA
Genome Projectsynaptic transmission, dopaminergic
GO:0001975
IEA
Genome Projectresponse to amphetamine
GO:0006469
IEA
Genome Projectnegative regulation of protein kinase activity
GO:0006606
IEA
Genome Projectprotein import into nucleus
GO:0006886
IEA
Genome Projectintracellular protein transport
GO:0006936
IEA
Genome Projectmuscle contraction
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007187
IDA
Genome ProjectG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007189
IDA
Genome Projectadenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190
IDA
Genome Projectactivation of adenylate cyclase activity
GO:0007191
IDA
Genome Projectadenylate cyclase-activating dopamine receptor signaling pathway
GO:0007212
IEA
Genome Projectdopamine receptor signaling pathway
GO:0007416
ISS
Genome Projectsynapse assembly
GO:0007606
IBA
Genome Projectsensory perception of chemical stimulus
GO:0007612
IBA
IEA
Genome Projectlearning
GO:0007613
IEA
Genome Projectmemory
GO:0007617
ISS
IEA
Genome Projectmating behavior
GO:0007625
IEA
Genome Projectgrooming behavior
GO:0007626
IEA
Genome Projectlocomotory behavior
GO:0007628
ISS
IEA
Genome Projectadult walking behavior
GO:0007631
IEA
Genome Projectfeeding behavior
GO:0008306
IEA
Genome Projectassociative learning
GO:0008542
ISS
IEA
Genome Projectvisual learning
GO:0010243
IEA
Genome Projectresponse to organonitrogen compound
GO:0010579
IBA
IEA
Genome Projectpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0014002
IEA
Genome Projectastrocyte development
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0014823
IEA
Genome Projectresponse to activity
GO:0015872
IEA
Genome Projectdopamine transport
GO:0019226
ISS
IEA
Genome Projecttransmission of nerve impulse
GO:0019228
IEA
Genome Projectneuronal action potential
GO:0019229
IEA
Genome Projectregulation of vasoconstriction
GO:0019722
IEA
Genome Projectcalcium-mediated signaling
GO:0021542
IEA
Genome Projectdentate gyrus development
GO:0021756
IEA
Genome Projectstriatum development
GO:0021766
IEA
Genome Projecthippocampus development
GO:0021769
IEA
Genome Projectorbitofrontal cortex development
GO:0021853
ISS
IEA
Genome Projectcerebral cortex GABAergic interneuron migration
GO:0030335
ISS
IEA
Genome Projectpositive regulation of cell migration
GO:0030336
IEA
Genome Projectnegative regulation of cell migration
GO:0030432
IEA
Genome Projectperistalsis
GO:0030819
IDA
IEA
Genome Projectpositive regulation of cAMP biosynthetic process
GO:0032094
IEA
Genome Projectresponse to food
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032526
IEA
Genome Projectresponse to retinoic acid
GO:0032869
IEA
Genome Projectcellular response to insulin stimulus
GO:0035094
IEA
Genome Projectresponse to nicotine
GO:0035106
IEA
Genome Projectoperant conditioning
GO:0035176
IEA
Genome Projectsocial behavior
GO:0036276
IEA
Genome Projectresponse to antidepressant
GO:0042053
IEA
Genome Projectregulation of dopamine metabolic process
GO:0042220
IEA
Genome Projectresponse to cocaine
GO:0042311
IEA
Genome Projectvasodilation
GO:0042321
IEA
Genome Projectnegative regulation of circadian sleep/wake cycle, sleep
GO:0042417
IC
Genome Projectdopamine metabolic process
GO:0042493
ISS
IEA
Genome Projectresponse to drug
GO:0042711
IEA
Genome Projectmaternal behavior
GO:0043200
IEA
Genome Projectresponse to amino acid
GO:0043268
ISS
Genome Projectpositive regulation of potassium ion transport
GO:0043269
IEA
Genome Projectregulation of ion transport
GO:0043278
IEA
Genome Projectresponse to morphine
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045838
IEA
Genome Projectpositive regulation of membrane potential
GO:0046323
IEA
Genome Projectglucose import
GO:0046959
IEA
Genome Projecthabituation
GO:0046960
IEA
Genome Projectsensitization
GO:0048148
IEA
Genome Projectbehavioral response to cocaine
GO:0048169
IEA
Genome Projectregulation of long-term neuronal synaptic plasticity
GO:0048545
IEA
Genome Projectresponse to steroid hormone
GO:0051281
IDA
Genome Projectpositive regulation of release of sequestered calcium ion into cytosol
GO:0051482
IDA
Genome Projectpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051584
IC
Genome Projectregulation of dopamine uptake involved in synaptic transmission
GO:0051968
ISS
IEA
Genome Projectpositive regulation of synaptic transmission, glutamatergic
GO:0060134
ISS
Genome Projectprepulse inhibition
GO:0060158
IDA, IGI
Genome Projectphospholipase C-activating dopamine receptor signaling pathway
GO:0060291
IEA
Genome Projectlong-term synaptic potentiation
GO:0060292
IEA
Genome Projectlong term synaptic depression
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:0071870
IDA
Genome Projectcellular response to catecholamine stimulus
GO:1900273
IEA
Genome Projectpositive regulation of long-term synaptic potentiation
GO:2000253
IEA
Genome Projectpositive regulation of feeding behavior

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001588
IDA, IMP
IEA
Genome Projectdopamine neurotransmitter receptor activity, coupled via Gs
GO:0001965
IEA
Genome ProjectG-protein alpha-subunit binding
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004952
IDA
IEA
Genome Projectdopamine neurotransmitter receptor activity
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008144
IEA
Genome Projectdrug binding
GO:0008227
IBA
Genome ProjectG-protein coupled amine receptor activity
GO:0019903
IEA
Genome Projectprotein phosphatase binding
GO:0031701
IEA
Genome Projectangiotensin receptor binding
GO:0031750
IEA
Genome ProjectD3 dopamine receptor binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0035240
IMP
Genome Projectdopamine binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity
GO:0051117
IEA
Genome ProjectATPase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005829
IDA
Genome Projectcytosol
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
IBA
IC, IEA
Genome Projectintegral component of plasma membrane
GO:0005901
IEA
Genome Projectcaveola
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0031513
IDA
Genome Projectnonmotile primary cilium
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043197
IEA
Genome Projectdendritic spine
GO:0043198
IEA
Genome Projectdendritic shaft
GO:0043679
IEA
Genome Projectaxon terminus
GO:0044326
IEA
Genome Projectdendritic spine neck
GO:0044327
IEA
Genome Projectdendritic spine head
GO:0060170
IDA
Genome Projectciliary membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000929Dopamine receptor family
IPR001413Dopamine D1 receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.