Gene: ENSG00000183454 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000183454
Transcript Identifier
ENST00000330684
Gene Type
Coding gene
Location
16 : 9763149-10180411 : negative

Family Information

Homologous gene family
HOM03P000932
(65 genes in 7 species)
specific family

Descriptions

gene_descr
glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Identifiers

Type Value
pidENSP00000332549
HGNC4585
UniprotQ12879
UniprotQ547U9

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001508
IEA
Genome Projectaction potential
GO:0006810
TAS, IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0007215
TAS
Genome Projectglutamate receptor signaling pathway
GO:0007268
TAS, IEA
Genome Projectsynaptic transmission
GO:0007611
TAS
Genome Projectlearning or memory
GO:0009416
IEA
Genome Projectresponse to light stimulus
GO:0009743
IEA
Genome Projectresponse to carbohydrate
GO:0010042
IEA
Genome Projectresponse to manganese ion
GO:0010942
IEA
Genome Projectpositive regulation of cell death
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0014075
IEA
Genome Projectresponse to amine
GO:0021510
IEA
Genome Projectspinal cord development
GO:0021766
IEA
Genome Projecthippocampus development
GO:0021987
IEA
Genome Projectcerebral cortex development
GO:0034220
IBA
IEA
Genome Projection transmembrane transport
GO:0034765
IEA
Genome Projectregulation of ion transmembrane transport
GO:0035235
IBA
IEA
Genome Projectionotropic glutamate receptor signaling pathway
GO:0035249
IBA
Genome Projectsynaptic transmission, glutamatergic
GO:0042220
IEA
Genome Projectresponse to cocaine
GO:0042493
IEA
Genome Projectresponse to drug
GO:0045471
IDA
IEA
Genome Projectresponse to ethanol
GO:0048169
IEA
Genome Projectregulation of long-term neuronal synaptic plasticity
GO:0048511
IEA
Genome Projectrhythmic process
GO:0051262
IEA
Genome Projectprotein tetramerization
GO:0051592
IEA
Genome Projectresponse to calcium ion
GO:0051597
IEA
Genome Projectresponse to methylmercury
GO:0051707
IEA
Genome Projectresponse to other organism
GO:0060079
IEA
Genome Projectexcitatory postsynaptic potential
GO:0060359
IEA
Genome Projectresponse to ammonium ion
GO:0060992
IEA
Genome Projectresponse to fungicide
GO:0071230
IEA
Genome Projectcellular response to amino acid stimulus
GO:0071286
IEA
Genome Projectcellular response to magnesium ion
GO:0071287
IEA
Genome Projectcellular response to manganese ion
GO:0071294
IEA
Genome Projectcellular response to zinc ion
GO:0071359
IEA
Genome Projectcellular response to dsRNA
GO:0071363
IEA
Genome Projectcellular response to growth factor stimulus
GO:0071396
IEA
Genome Projectcellular response to lipid

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004872
IEA
Genome Projectreceptor activity
GO:0004970
IEA
Genome Projectionotropic glutamate receptor activity
GO:0004972
TAS, IEA
Genome ProjectNMDA glutamate receptor activity
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005216
IEA
Genome Projection channel activity
GO:0005234
IBA
IEA
Genome Projectextracellular-glutamate-gated ion channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
ISS
IEA
Genome Projectzinc ion binding
GO:0016595
IEA
Genome Projectglutamate binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0022843
IEA
Genome Projectvoltage-gated cation channel activity
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0035254
IEA
Genome Projectglutamate receptor binding
GO:0042165
IEA
Genome Projectneurotransmitter binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity
GO:0046983
IEA
Genome Projectprotein dimerization activity
GO:0050839
IEA
Genome Projectcell adhesion molecule binding
GO:0051117
IEA
Genome ProjectATPase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IBA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0009986
ISS
Genome Projectcell surface
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0017146
IDA
IEA
Genome ProjectNMDA selective glutamate receptor complex
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
IBA
Genome Projectdendrite
GO:0043195
IEA
Genome Projectterminal bouton
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IBA
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001320Ionotropic glutamate receptor
IPR001508Ionotropic glutamate receptor, metazoa
IPR001828Receptor, ligand binding region
IPR018884Glutamate [NMDA] receptor, epsilon subunit, C-terminal
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
IPR028082Periplasmic binding protein-like I

No MapMan annotations defined for this gene.