Gene: ENSG00000183087 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000183087
Transcript Identifier
ENST00000327773
Gene Type
Coding gene
Location
13 : 113820864-113863920 : negative

Family Information

Homologous gene family
HOM03P000383
(115 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P035166
(3 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
growth arrest-specific 6

Identifiers

Type Value
pidENSP00000331831
HGNC4168
UniprotQ14393

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001764
IEA
Genome Projectneuron migration
GO:0001934
IDA
ISS
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0001961
IMP
Genome Projectpositive regulation of cytokine-mediated signaling pathway
GO:0002576
TAS
Genome Projectplatelet degranulation
GO:0003104
ISS
IEA
Genome Projectpositive regulation of glomerular filtration
GO:0006468
IDA
Genome Projectprotein phosphorylation
GO:0006508
TAS
Genome Projectproteolysis
GO:0006909
IDA
Genome Projectphagocytosis
GO:0007050
TAS
Genome Projectcell cycle arrest
GO:0007155
TAS
Genome Projectcell adhesion
GO:0007165
IDA
TAS, IEA
Genome Projectsignal transduction
GO:0007167
IEA
Genome Projectenzyme linked receptor protein signaling pathway
GO:0007596
TAS, IEA
Genome Projectblood coagulation
GO:0008283
TAS
Genome Projectcell proliferation
GO:0009267
IEA
Genome Projectcellular response to starvation
GO:0010628
IDA
Genome Projectpositive regulation of gene expression
GO:0010804
IDA
Genome Projectnegative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010934
IEA
Genome Projectmacrophage cytokine production
GO:0016477
TAS
Genome Projectcell migration
GO:0017187
TAS
Genome Projectpeptidyl-glutamic acid carboxylation
GO:0018105
IDA
Genome Projectpeptidyl-serine phosphorylation
GO:0019064
IDA
Genome Projectfusion of virus membrane with host plasma membrane
GO:0019079
IDA
Genome Projectviral genome replication
GO:0030168
TAS
Genome Projectplatelet activation
GO:0031100
IEA
Genome Projectorgan regeneration
GO:0031589
IEA
Genome Projectcell-substrate adhesion
GO:0032008
ISS
IEA
Genome Projectpositive regulation of TOR signaling
GO:0032148
ISS
IEA
Genome Projectactivation of protein kinase B activity
GO:0032689
IDA
Genome Projectnegative regulation of interferon-gamma production
GO:0032715
IDA
Genome Projectnegative regulation of interleukin-6 production
GO:0032720
IDA
Genome Projectnegative regulation of tumor necrosis factor production
GO:0032825
IDA
Genome Projectpositive regulation of natural killer cell differentiation
GO:0033138
IDA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0033159
IDA
Genome Projectnegative regulation of protein import into nucleus, translocation
GO:0035457
IDA
Genome Projectcellular response to interferon-alpha
GO:0035690
IDA
IEA
Genome Projectcellular response to drug
GO:0035754
IDA
Genome ProjectB cell chemotaxis
GO:0040008
IEA
Genome Projectregulation of growth
GO:0043066
IDA
Genome Projectnegative regulation of apoptotic process
GO:0043154
IDA
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043277
IDA
Genome Projectapoptotic cell clearance
GO:0043433
IDA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0043491
IDA
Genome Projectprotein kinase B signaling
GO:0043687
TAS
Genome Projectpost-translational protein modification
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0045860
IDA
Genome Projectpositive regulation of protein kinase activity
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0046718
IDA
Genome Projectviral entry into host cell
GO:0046813
IDA
Genome Projectreceptor-mediated virion attachment to host cell
GO:0046827
IDA
Genome Projectpositive regulation of protein export from nucleus
GO:0048146
IDA
Genome Projectpositive regulation of fibroblast proliferation
GO:0050711
IDA
Genome Projectnegative regulation of interleukin-1 secretion
GO:0050766
IDA
Genome Projectpositive regulation of phagocytosis
GO:0050900
TAS
Genome Projectleukocyte migration
GO:0051897
IDA
IEA
Genome Projectpositive regulation of protein kinase B signaling
GO:0061098
IDA
Genome Projectpositive regulation of protein tyrosine kinase activity
GO:0070168
IDA
Genome Projectnegative regulation of biomineral tissue development
GO:0070374
IDA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070527
TAS
Genome Projectplatelet aggregation
GO:0070588
IDA
Genome Projectcalcium ion transmembrane transport
GO:0071307
IDA
Genome Projectcellular response to vitamin K
GO:0071333
ISS
IEA
Genome Projectcellular response to glucose stimulus
GO:0071363
IEA
Genome Projectcellular response to growth factor stimulus
GO:0072661
IDA
Genome Projectprotein targeting to plasma membrane
GO:0085029
ISS
IEA
Genome Projectextracellular matrix assembly
GO:0097028
IEP
Genome Projectdendritic cell differentiation
GO:0097241
IDA
Genome Projecthematopoietic stem cell migration to bone marrow
GO:1900142
IDA
Genome Projectnegative regulation of oligodendrocyte apoptotic process
GO:1900165
IDA
Genome Projectnegative regulation of interleukin-6 secretion
GO:2000270
IDA
Genome Projectnegative regulation of fibroblast apoptotic process
GO:2000352
IDA
Genome Projectnegative regulation of endothelial cell apoptotic process
GO:2000510
IDA
Genome Projectpositive regulation of dendritic cell chemotaxis
GO:2000533
ISS
IEA
Genome Projectnegative regulation of renal albumin absorption
GO:2000669
IDA
Genome Projectnegative regulation of dendritic cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001786
IDA
Genome Projectphosphatidylserine binding
GO:0005102
IDA, IPI
Genome Projectreceptor binding
GO:0005245
IDA
Genome Projectvoltage-gated calcium channel activity
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0030296
IDA
Genome Projectprotein tyrosine kinase activator activity
GO:0030971
IPI
Genome Projectreceptor tyrosine kinase binding
GO:0043027
IDA
Genome Projectcysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0048018
IDA
Genome Projectreceptor agonist activity
GO:0060090
IDA
Genome Projectbinding, bridging

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005622
IEA
Genome Projectintracellular
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005788
TAS
Genome Projectendoplasmic reticulum lumen
GO:0005796
TAS
Genome ProjectGolgi lumen
GO:0031093
TAS
Genome Projectplatelet alpha granule lumen
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000152EGF-type aspartate/asparagine hydroxylation site
IPR000294Gamma-carboxyglutamic acid-rich (GLA) domain
IPR000742EGF-like domain
IPR001791Laminin G domain
IPR001881EGF-like calcium-binding domain
IPR009030Growth factor receptor cysteine-rich domain
IPR013032EGF-like, conserved site
IPR013320Concanavalin A-like lectin/glucanase domain
IPR017857Coagulation factor, subgroup, Gla domain
IPR018097EGF-like calcium-binding, conserved site

No MapMan annotations defined for this gene.