Gene: ENSG00000181467 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000181467
Transcript Identifier
ENST00000323534
Gene Type
Coding gene
Location
3 : 153162694-153163245 : positive

Family Information

Homologous gene family
HOM03P000013
(1389 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P069677
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
RAP2B, member of RAS oncogene family

Identifiers

Type Value
pidENSP00000319096
HGNC9862
UniprotP61225

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
TAS, IEA
Genome Projectsignal transduction
GO:0007264
IEA
Genome Projectsmall GTPase mediated signal transduction
GO:0030168
IDA
Genome Projectplatelet activation
GO:0030336
IEA
Genome Projectnegative regulation of cell migration
GO:0031954
IEA
Genome Projectpositive regulation of protein autophosphorylation
GO:0032486
ISS
IEA
Genome ProjectRap protein signal transduction
GO:0061097
ISS
IEA
Genome Projectregulation of protein tyrosine kinase activity
GO:0070527
IDA
Genome Projectplatelet aggregation
GO:0030033
IMP
Genome Projectmicrovillus assembly
GO:0090557
IMP
Genome Projectestablishment of endothelial intestinal barrier

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005525
IDA
TAS, IEA
Genome ProjectGTP binding
GO:0019003
IDA
Genome ProjectGDP binding
GO:0019904
IEA
Genome Projectprotein domain specific binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005768
IEA
Genome Projectendosome
GO:0005829
IDA
Genome Projectcytosol
GO:0005886
IDA
Genome Projectplasma membrane
GO:0005923
IDA
Genome Projectbicellular tight junction
GO:0016020
IMP
IEA
Genome Projectmembrane
GO:0044291
IDA
Genome Projectcell-cell contact zone
GO:0045121
IMP
Genome Projectmembrane raft
GO:0055037
IEA
Genome Projectrecycling endosome
GO:0055038
ISS
IEA
Genome Projectrecycling endosome membrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001806Small GTPase superfamily
IPR005225Small GTP-binding protein domain
IPR020849Small GTPase superfamily, Ras type
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.