Gene: ENSG00000181072 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000181072
Transcript Identifier
ENST00000401861
Gene Type
Coding gene
Location
7 : 137014866-137016266 : positive

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P024233
(4 genes in 2 species)
specific family

Descriptions

gene_descr
cholinergic receptor, muscarinic 2

Identifiers

Type Value
pidENSP00000384401
HGNC1951
UniprotP08172
UniprotA4D1Q0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006940
IBA
IEA
Genome Projectregulation of smooth muscle contraction
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
TAS, IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007213
IDA
IEA
Genome ProjectG-protein coupled acetylcholine receptor signaling pathway
GO:0008016
TAS, IEA
Genome Projectregulation of heart contraction
GO:0007187
TAS
Genome ProjectG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007188
TAS
Genome Projectadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007197
IBA
Genome Projectadenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
GO:0007207
TAS
Genome Projectphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0007271
IBA
Genome Projectsynaptic transmission, cholinergic
GO:0007399
TAS
Genome Projectnervous system development
GO:0007606
IBA
Genome Projectsensory perception of chemical stimulus
GO:0009615
IEP
Genome Projectresponse to virus
GO:0010579
IBA
Genome Projectpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0008144
IEA
Genome Projectdrug binding
GO:0016907
IDA
TAS, IEA
Genome ProjectG-protein coupled acetylcholine receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
IDA
TAS, IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
IEA
Genome Projectdendrite
GO:0032279
IEA
Genome Projectasymmetric synapse
GO:0032280
IEA
Genome Projectsymmetric synapse
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043679
IEA
Genome Projectaxon terminus
GO:0045202
IBA
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000995Muscarinic acetylcholine receptor family
IPR001065Muscarinic acetylcholine receptor M2
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.