Gene: ENSG00000180772 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000180772
Transcript Identifier
ENST00000371906
Gene Type
Coding gene
Location
X : 116172281-116173372 : positive

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P064372
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
angiotensin II receptor, type 2

Identifiers

Type Value
pidENSP00000360973
HGNC338
UniprotP50052

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001822
IEA
Genome Projectkidney development
GO:0001974
TAS
Genome Projectblood vessel remodeling
GO:0001991
ISS
IEA
Genome Projectregulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0002018
IEA
Genome Projectrenin-angiotensin regulation of aldosterone production
GO:0002033
IEA
Genome Projectvasodilation by angiotensin involved in regulation of systemic arterial blood pressure
GO:0002035
IEA
Genome Projectbrain renin-angiotensin system
GO:0006883
IEA
Genome Projectcellular sodium ion homeostasis
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
IDA
TAS
Genome Projectcell surface receptor signaling pathway
GO:0007186
IC, IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007199
ISS
IEA
Genome ProjectG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0007263
TAS, IC
Genome Projectnitric oxide mediated signal transduction
GO:0007420
NAS
Genome Projectbrain development
GO:0008217
TAS
Genome Projectregulation of blood pressure
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0010243
IEA
Genome Projectresponse to organonitrogen compound
GO:0010459
ISS
IEA
Genome Projectnegative regulation of heart rate
GO:0010700
IEA
Genome Projectnegative regulation of norepinephrine secretion
GO:0021695
IEA
Genome Projectcerebellar cortex development
GO:0030308
TAS
Genome Projectnegative regulation of cell growth
GO:0032304
IEA
Genome Projectnegative regulation of icosanoid secretion
GO:0032516
IDA
Genome Projectpositive regulation of phosphoprotein phosphatase activity
GO:0035556
ISS
IEA
Genome Projectintracellular signal transduction
GO:0035566
IEA
Genome Projectregulation of metanephros size
GO:0035640
IEA
Genome Projectexploration behavior
GO:0035815
IEA
Genome Projectpositive regulation of renal sodium excretion
GO:0035932
IEA
Genome Projectaldosterone secretion
GO:0038166
IPI
TAS, IEA
Genome Projectangiotensin-activated signaling pathway
GO:0042312
IEA
Genome Projectregulation of vasodilation
GO:0042416
IEA
Genome Projectdopamine biosynthetic process
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0042990
IEA
Genome Projectregulation of transcription factor import into nucleus
GO:0043537
NAS
Genome Projectnegative regulation of blood vessel endothelial cell migration
GO:0045429
IC
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045909
IDA
IEA
Genome Projectpositive regulation of vasodilation
GO:0048147
IEA
Genome Projectnegative regulation of fibroblast proliferation
GO:0050715
IEA
Genome Projectpositive regulation of cytokine secretion
GO:0051000
ISS
IEA
Genome Projectpositive regulation of nitric-oxide synthase activity
GO:0051387
IMP
Genome Projectnegative regulation of neurotrophin TRK receptor signaling pathway
GO:0060993
IEA
Genome Projectkidney morphogenesis
GO:0061049
IEA
Genome Projectcell growth involved in cardiac muscle cell development
GO:0071549
IEA
Genome Projectcellular response to dexamethasone stimulus
GO:0072300
IEA
Genome Projectpositive regulation of metanephric glomerulus development
GO:0090190
IEA
Genome Projectpositive regulation of branching involved in ureteric bud morphogenesis
GO:1900116
TAS
Genome Projectextracellular negative regulation of signal transduction
GO:2001238
IMP
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004945
IPI
TAS, IEA
Genome Projectangiotensin type II receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IEA
Genome Projecttranscription factor binding
GO:0017046
IEA
Genome Projectpeptide hormone binding
GO:0048019
TAS
Genome Projectreceptor antagonist activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS
Genome Projectextracellular region
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS, IC
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000147Angiotensin II receptor type 2
IPR000248Angiotensin II receptor family
IPR000276G protein-coupled receptor, rhodopsin-like
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.