Gene: ENSG00000180176 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000180176
Transcript Identifier
ENST00000381178
Gene Type
Coding gene
Location
11 : 2164233-2171786 : negative

Family Information

Homologous gene family
HOM03P003508
(28 genes in 18 species)
specific family
Orthologous gene family
ORTHO03P029260
(4 genes in 4 species)
specific family

Descriptions

gene_descr
tyrosine hydroxylase

Identifiers

Type Value
pidENSP00000370571
HGNC11782
UniprotP07101

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IDA
IEA
Genome Projectresponse to hypoxia
GO:0001963
ISS
IEA
Genome Projectsynaptic transmission, dopaminergic
GO:0001975
IEA
Genome Projectresponse to amphetamine
GO:0003007
NAS
Genome Projectheart morphogenesis
GO:0006585
NAS, IEA
Genome Projectdopamine biosynthetic process from tyrosine
GO:0006631
IEA
Genome Projectfatty acid metabolic process
GO:0006665
IEA
Genome Projectsphingolipid metabolic process
GO:0007507
ISS
IEA
Genome Projectheart development
GO:0007601
ISS
IEA
Genome Projectvisual perception
GO:0007605
IEA
Genome Projectsensory perception of sound
GO:0007612
ISS
IEA
Genome Projectlearning
GO:0007613
ISS
IEA
Genome Projectmemory
GO:0007617
IEA
Genome Projectmating behavior
GO:0007626
ISS
IEA
Genome Projectlocomotory behavior
GO:0008016
ISS
IEA
Genome Projectregulation of heart contraction
GO:0009072
IEA
Genome Projectaromatic amino acid family metabolic process
GO:0009414
IEA
Genome Projectresponse to water deprivation
GO:0009416
IEA
Genome Projectresponse to light stimulus
GO:0009635
IEA
Genome Projectresponse to herbicide
GO:0009651
IEA
Genome Projectresponse to salt stress
GO:0009653
TAS
Genome Projectanatomical structure morphogenesis
GO:0009887
ISS
IEA
Genome Projectorgan morphogenesis
GO:0010038
IEA
Genome Projectresponse to metal ion
GO:0010043
IEA
Genome Projectresponse to zinc ion
GO:0010259
IEA
Genome Projectmulticellular organismal aging
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0014823
IEA
Genome Projectresponse to activity
GO:0015842
IEA
Genome Projectsynaptic vesicle amine transport
GO:0016137
IEA
Genome Projectglycoside metabolic process
GO:0017085
IEA
Genome Projectresponse to insecticide
GO:0018963
IEA
Genome Projectphthalate metabolic process
GO:0021987
IEA
Genome Projectcerebral cortex development
GO:0031667
IEA
Genome Projectresponse to nutrient levels
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0033076
IEA
Genome Projectisoquinoline alkaloid metabolic process
GO:0034641
TAS
Genome Projectcellular nitrogen compound metabolic process
GO:0035094
IEA
Genome Projectresponse to nicotine
GO:0035176
IEA
Genome Projectsocial behavior
GO:0035690
IEA
Genome Projectcellular response to drug
GO:0035900
IEA
Genome Projectresponse to isolation stress
GO:0035902
IEA
Genome Projectresponse to immobilization stress
GO:0042136
IEA
Genome Projectneurotransmitter biosynthetic process
GO:0042214
IEA
Genome Projectterpene metabolic process
GO:0042416
IDA
IEA
Genome Projectdopamine biosynthetic process
GO:0042418
IDA
Genome Projectepinephrine biosynthetic process
GO:0042421
IDA
Genome Projectnorepinephrine biosynthetic process
GO:0042423
TAS, IEA
Genome Projectcatecholamine biosynthetic process
GO:0042462
ISS
IEA
Genome Projecteye photoreceptor cell development
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042745
IEA
Genome Projectcircadian sleep/wake cycle
GO:0042755
IEA
Genome Projecteating behavior
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0043473
TAS
Genome Projectpigmentation
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045471
IDA
IEA
Genome Projectresponse to ethanol
GO:0045472
IEA
Genome Projectresponse to ether
GO:0046684
IEA
Genome Projectresponse to pyrethroid
GO:0048545
IEA
Genome Projectresponse to steroid hormone
GO:0048596
ISS
IEA
Genome Projectembryonic camera-type eye morphogenesis
GO:0050890
IEA
Genome Projectcognition
GO:0051412
IEA
Genome Projectresponse to corticosterone
GO:0051602
IEA
Genome Projectresponse to electrical stimulus
GO:0052314
IEA
Genome Projectphytoalexin metabolic process
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0070848
IEA
Genome Projectresponse to growth factor
GO:0071287
IEA
Genome Projectcellular response to manganese ion
GO:0071312
IEA
Genome Projectcellular response to alkaloid
GO:0071316
IEA
Genome Projectcellular response to nicotine
GO:0071333
IEA
Genome Projectcellular response to glucose stimulus
GO:0071363
IEA
Genome Projectcellular response to growth factor stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004497
IEA
Genome Projectmonooxygenase activity
GO:0004511
IDA
TAS, IEA
Genome Projecttyrosine 3-monooxygenase activity
GO:0005506
IEA
Genome Projectiron ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008198
IEA
Genome Projectferrous iron binding
GO:0008199
IEA
Genome Projectferric iron binding
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016597
IEA
Genome Projectamino acid binding
GO:0016714
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
GO:0019825
IEA
Genome Projectoxygen binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0034617
IEA
Genome Projecttetrahydrobiopterin binding
GO:0035240
IEA
Genome Projectdopamine binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISS
IEA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005790
IDA
Genome Projectsmooth endoplasmic reticulum
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0008021
IEA
Genome Projectsynaptic vesicle
GO:0009898
IDA
Genome Projectcytoplasmic side of plasma membrane
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0030659
IEA
Genome Projectcytoplasmic vesicle membrane
GO:0031410
IDA
Genome Projectcytoplasmic vesicle
GO:0033162
IDA
Genome Projectmelanosome membrane
GO:0043005
IDA
IEA
Genome Projectneuron projection
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043195
IEA
Genome Projectterminal bouton
GO:0043204
ISS
IEA
Genome Projectperikaryon

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001273Aromatic amino acid hydroxylase
IPR005962Tyrosine 3-monooxygenase
IPR018301Aromatic amino acid hydroxylase, iron/copper binding site
IPR019773Tyrosine 3-monooxygenase-like
IPR019774Aromatic amino acid hydroxylase, C-terminal
IPR021164Tyrosine hydroxylase, conserved site

No MapMan annotations defined for this gene.