Gene: ENSG00000179915 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000179915
Transcript Identifier
ENST00000404971
Gene Type
Coding gene
Location
2 : 49921944-51028273 : negative

Family Information

Homologous gene family
HOM03P006322
(14 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P009378
(9 genes in 4 species)
specific family

Descriptions

gene_descr
neurexin 1

Identifiers

Type Value
pidENSP00000385142
HGNC8008
UniprotQ9ULB1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007158
TAS
Genome Projectneuron cell-cell adhesion
GO:0007268
ISS
IEA
Genome Projectsynaptic transmission
GO:0007269
ISS
IEA
Genome Projectneurotransmitter secretion
GO:0007411
TAS
Genome Projectaxon guidance
GO:0007416
ISS
IEA
Genome Projectsynapse assembly
GO:0007612
IMP
Genome Projectlearning
GO:0030198
TAS
Genome Projectextracellular matrix organization
GO:0030534
IMP
Genome Projectadult behavior
GO:0035176
IMP
Genome Projectsocial behavior
GO:0042297
IMP
Genome Projectvocal learning
GO:0050885
IMP
ISS
Genome Projectneuromuscular process controlling balance
GO:0051965
ISS
IEA
Genome Projectpositive regulation of synapse assembly
GO:0051968
ISS
IEA
Genome Projectpositive regulation of synaptic transmission, glutamatergic
GO:0060134
IEA
Genome Projectprepulse inhibition
GO:0061178
IEA
Genome Projectregulation of insulin secretion involved in cellular response to glucose stimulus
GO:0071625
IMP
Genome Projectvocalization behavior
GO:0090129
ISS
IEA
Genome Projectpositive regulation of synapse maturation
GO:0097104
ISS
IEA
Genome Projectpostsynaptic membrane assembly
GO:0097116
ISS
IEA
Genome Projectgephyrin clustering involved in postsynaptic density assembly
GO:0097118
ISS
IEA
Genome Projectneuroligin clustering involved in postsynaptic membrane assembly
GO:0097119
ISS
IEA
Genome Projectpostsynaptic density protein 95 clustering
GO:2000463
ISS
IEA
Genome Projectpositive regulation of excitatory postsynaptic potential
GO:2000821
IEA
Genome Projectregulation of grooming behavior

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004872
TAS
Genome Projectreceptor activity
GO:0005246
ISS
IEA
Genome Projectcalcium channel regulator activity
GO:0005509
ISS
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0033130
ISS
IEA
Genome Projectacetylcholine receptor binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0050839
ISS
IEA
Genome Projectcell adhesion molecule binding
GO:0097109
ISS
IEA
Genome Projectneuroligin family protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
ISS
IEA
Genome Projectendoplasmic reticulum
GO:0005886
ISS
IC, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0031965
ISS
IEA
Genome Projectnuclear membrane
GO:0031982
ISS
IEA
Genome Projectvesicle
GO:0042734
ISS
IEA
Genome Projectpresynaptic membrane
GO:0043025
ISS
IEA
Genome Projectneuronal cell body
GO:0043234
IEA
Genome Projectprotein complex
GO:0045202
IEA
Genome Projectsynapse

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000152EGF-type aspartate/asparagine hydroxylation site
IPR000742EGF-like domain
IPR001791Laminin G domain
IPR003585Neurexin/syndecan/glycophorin C
IPR013320Concanavalin A-like lectin/glucanase domain
IPR027789Syndecan/Neurexin domain
IPR029824Neurexin-1

No MapMan annotations defined for this gene.