Gene: ENSG00000179477 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000179477
Transcript Identifier
ENST00000319144
Gene Type
Coding gene
Location
17 : 8072771-8087442 : negative

Family Information

Homologous gene family
HOM03P000704
(78 genes in 15 species)
specific family
Orthologous gene family
ORTHO03P000181
(65 genes in 15 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
arachidonate 12-lipoxygenase, 12R type

Identifiers

Type Value
pidENSP00000315167
HGNC430
UniprotO75342

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006497
ISS
IEA
Genome Projectprotein lipidation
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006631
IEA
Genome Projectfatty acid metabolic process
GO:0006665
IDA
IEA
Genome Projectsphingolipid metabolic process
GO:0010628
IMP
Genome Projectpositive regulation of gene expression
GO:0019369
IMP
ISS
TAS
Genome Projectarachidonic acid metabolic process
GO:0019372
IDA, IMP
TAS
Genome Projectlipoxygenase pathway
GO:0043410
IDA
Genome Projectpositive regulation of MAPK cascade
GO:0043651
ISS
IEA
Genome Projectlinoleic acid metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0046513
ISS
IEA
Genome Projectceramide biosynthetic process
GO:0051122
ISS
Genome Projecthepoxilin biosynthetic process
GO:0055114
IDA, IMP
IEA
Genome Projectoxidation-reduction process
GO:0061436
ISS
IEA
Genome Projectestablishment of skin barrier
GO:0070257
IMP
Genome Projectpositive regulation of mucus secretion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004052
IMP
TAS
Genome Projectarachidonate 12-lipoxygenase activity
GO:0005506
IEA
Genome Projectiron ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016702
IDA
IEA
Genome Projectoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051213
IEA
Genome Projectdioxygenase activity
GO:1990136
ISS
IEA
Genome Projectlinoleate 9S-lipoxygenase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000907Lipoxygenase
IPR001024PLAT/LH2 domain
IPR001885Lipoxygenase, mammalian
IPR013819Lipoxygenase, C-terminal
IPR020833Lipoxygenase, iron binding site
IPR020834Lipoxygenase, conserved site

No MapMan annotations defined for this gene.