Gene: ENSG00000177606 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000177606
Transcript Identifier
ENST00000371222
Gene Type
Coding gene
Location
1 : 58782075-58783070 : negative

Family Information

Homologous gene family
HOM03P011962
(7 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P072367
(2 genes in 2 species)
specific family

Descriptions

gene_descr
jun proto-oncogene

Identifiers

Type Value
pidENSP00000360266
HGNC6204
UniprotP05412

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001774
IEA
Genome Projectmicroglial cell activation
GO:0001836
IEA
Genome Projectrelease of cytochrome c from mitochondria
GO:0001889
IEA
Genome Projectliver development
GO:0001938
IEA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002755
TAS
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0003151
IEA
Genome Projectoutflow tract morphogenesis
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007179
IDA
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007184
IDA
Genome ProjectSMAD protein import into nucleus
GO:0007568
IEA
Genome Projectaging
GO:0007612
IEA
Genome Projectlearning
GO:0007623
IEA
Genome Projectcircadian rhythm
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009314
IBA
IEA
Genome Projectresponse to radiation
GO:0009612
IBA
IEA
Genome Projectresponse to mechanical stimulus
GO:0009987
IEA
Genome Projectcellular process
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010941
IBA
Genome Projectregulation of cell death
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0030224
IEA
Genome Projectmonocyte differentiation
GO:0031103
IEA
Genome Projectaxon regeneration
GO:0031953
IEA
Genome Projectnegative regulation of protein autophosphorylation
GO:0032496
IBA
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032870
IBA
Genome Projectcellular response to hormone stimulus
GO:0034097
IBA
IEA
Genome Projectresponse to cytokine
GO:0034134
TAS
Genome Projecttoll-like receptor 2 signaling pathway
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0034146
TAS
Genome Projecttoll-like receptor 5 signaling pathway
GO:0034162
TAS
Genome Projecttoll-like receptor 9 signaling pathway
GO:0034166
TAS
Genome Projecttoll-like receptor 10 signaling pathway
GO:0035026
IEA
Genome Projectleading edge cell differentiation
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0035994
IEA
Genome Projectresponse to muscle stretch
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0038123
TAS
Genome Projecttoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124
TAS
Genome Projecttoll-like receptor TLR6:TLR2 signaling pathway
GO:0042127
IBA
Genome Projectregulation of cell proliferation
GO:0042493
IBA
IEA
Genome Projectresponse to drug
GO:0042542
IEA
Genome Projectresponse to hydrogen peroxide
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043392
IDA
Genome Projectnegative regulation of DNA binding
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0043547
IDA
Genome Projectpositive regulation of GTPase activity
GO:0043922
IDA
Genome Projectnegative regulation by host of viral transcription
GO:0043923
IDA
Genome Projectpositive regulation by host of viral transcription
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045597
IBA
Genome Projectpositive regulation of cell differentiation
GO:0045657
IEA
Genome Projectpositive regulation of monocyte differentiation
GO:0045740
IEA
Genome Projectpositive regulation of DNA replication
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
IC, IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048146
IEA
Genome Projectpositive regulation of fibroblast proliferation
GO:0048661
IEA
Genome Projectpositive regulation of smooth muscle cell proliferation
GO:0051090
TAS
Genome Projectregulation of sequence-specific DNA binding transcription factor activity
GO:0051365
IEA
Genome Projectcellular response to potassium ion starvation
GO:0051403
TAS
Genome Projectstress-activated MAPK cascade
GO:0051591
IBA
IEA
Genome Projectresponse to cAMP
GO:0051726
IBA
IEA
Genome Projectregulation of cell cycle
GO:0051899
IEA
Genome Projectmembrane depolarization
GO:0060395
IDA
Genome ProjectSMAD protein signal transduction
GO:0071277
IEA
Genome Projectcellular response to calcium ion
GO:1990441
IMP
Genome Projectnegative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:2000144
IDA
Genome Projectpositive regulation of DNA-templated transcription, initiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
IBA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980
IDA
Genome ProjectRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981
IC
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001077
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001102
IPI
Genome ProjectRNA polymerase II activating transcription factor binding
GO:0001190
IC
Genome Projecttranscriptional activator activity, RNA polymerase II transcription factor binding
GO:0003677
TAS, IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003690
IEA
Genome Projectdouble-stranded DNA binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IDA
IC
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003713
IDA
Genome Projecttranscription coactivator activity
GO:0005096
IDA
Genome ProjectGTPase activator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
IEA
Genome Projecttranscription factor binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0035497
IDA
Genome ProjectcAMP response element binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0070412
IPI
Genome ProjectR-SMAD binding
GO:0071837
IEA
Genome ProjectHMG box domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000228
TAS
Genome Projectnuclear chromosome
GO:0000790
IEA
Genome Projectnuclear chromatin
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005667
IBA
IEA
Genome Projecttranscription factor complex
GO:0005719
IDA
Genome Projectnuclear euchromatin
GO:0005829
IEA
Genome Projectcytosol
GO:0017053
IEA
Genome Projecttranscriptional repressor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002112Transcription factor Jun
IPR004827Basic-leucine zipper domain
IPR005643Jun-like transcription factor
IPR008917Transcription factor, Skn-1-like, DNA-binding domain
IPR015558Transcription Factor c-Jun/v-Jun

No MapMan annotations defined for this gene.