Gene: ENSG00000177426 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000177426
Transcript Identifier
ENST00000330513
Gene Type
Coding gene
Location
18 : 3451980-3457940 : positive

Family Information

Homologous gene family
HOM03P000614
(85 genes in 27 species)
specific family
Orthologous gene family
ORTHO03P064400
(2 genes in 2 species)
specific family

Descriptions

gene_descr
TGFB-induced factor homeobox 1

Identifiers

Type Value
pidENSP00000327959
HGNC11776
UniprotQ15583

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA, IMP
TAS
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001843
IEA
Genome Projectneural tube closure
GO:0006351
TAS, IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006367
TAS
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0007179
TAS
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007275
TAS
Genome Projectmulticellular organismal development
GO:0007368
IEA
Genome Projectdetermination of left/right symmetry
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009953
IEA
Genome Projectdorsal/ventral pattern formation
GO:0010467
TAS
Genome Projectgene expression
GO:0010470
IEA
Genome Projectregulation of gastrulation
GO:0010629
IEA
Genome Projectnegative regulation of gene expression
GO:0038092
IEA
Genome Projectnodal signaling pathway
GO:0042493
IEA
Genome Projectresponse to drug
GO:0045666
IEA
Genome Projectpositive regulation of neuron differentiation
GO:0048146
IEA
Genome Projectpositive regulation of fibroblast proliferation
GO:0048387
IEA
Genome Projectnegative regulation of retinoic acid receptor signaling pathway
GO:0060041
IEA
Genome Projectretina development in camera-type eye
GO:0071363
IEA
Genome Projectcellular response to growth factor stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
IDA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078
IDA, IMP
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
TAS
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003714
TAS
Genome Projecttranscription corepressor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0070410
IEA
Genome Projectco-SMAD binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001356Homeobox domain
IPR008422Homeobox KN domain
IPR009057Homeodomain-like

No MapMan annotations defined for this gene.