Gene: ENSG00000177301 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000177301
Transcript Identifier
ENST00000316361
Gene Type
Coding gene
Location
1 : 110603283-110604782 : negative

Family Information

Homologous gene family
HOM03P000312
(130 genes in 21 species)
specific family
Orthologous gene family
ORTHO03P004389
(19 genes in 6 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
potassium channel, voltage gated shaker related subfamily A, member 2

Identifiers

Type Value
pidENSP00000314520
HGNC6220
UniprotP16389

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006813
TAS, IEA
Genome Projectpotassium ion transport
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0014059
ISS
IEA
Genome Projectregulation of dopamine secretion
GO:0019228
ISS
IEA
Genome Projectneuronal action potential
GO:0019233
ISS
IEA
Genome Projectsensory perception of pain
GO:0021633
IEA
Genome Projectoptic nerve structural organization
GO:0034765
IEA
Genome Projectregulation of ion transmembrane transport
GO:0045188
IEA
Genome Projectregulation of circadian sleep/wake cycle, non-REM sleep
GO:0051259
IEA
Genome Projectprotein oligomerization
GO:0051260
IEA
Genome Projectprotein homooligomerization
GO:0055085
IEA
Genome Projecttransmembrane transport
GO:0071805
IMP
ISS
IEA
Genome Projectpotassium ion transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005216
IEA
Genome Projection channel activity
GO:0005244
IEA
Genome Projectvoltage-gated ion channel activity
GO:0005249
IMP
ISS
TAS, IEA
Genome Projectvoltage-gated potassium channel activity
GO:0005251
ISS
TAS
Genome Projectdelayed rectifier potassium channel activity
GO:0005267
TAS, IEA
Genome Projectpotassium channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0015271
IEA
Genome Projectoutward rectifier potassium channel activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
IMP
IEA
Genome Projectintegral component of plasma membrane
GO:0008076
IDA
TAS, IEA
Genome Projectvoltage-gated potassium channel complex
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030027
ISS
IEA
Genome Projectlamellipodium
GO:0030054
IEA
Genome Projectcell junction
GO:0030424
ISS
IEA
Genome Projectaxon
GO:0030425
ISS
IEA
Genome Projectdendrite
GO:0031258
IEA
Genome Projectlamellipodium membrane
GO:0032809
ISS
IEA
Genome Projectneuronal cell body membrane
GO:0034705
IEA
Genome Projectpotassium channel complex
GO:0042734
IEA
Genome Projectpresynaptic membrane
GO:0042995
IEA
Genome Projectcell projection
GO:0043005
IEA
Genome Projectneuron projection
GO:0043204
ISS
IEA
Genome Projectperikaryon
GO:0043679
ISS
IEA
Genome Projectaxon terminus
GO:0044224
ISS
IEA
Genome Projectjuxtaparanode region of axon
GO:0045202
IEA
Genome Projectsynapse

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000210BTB/POZ domain
IPR003131Potassium channel tetramerisation-type BTB domain
IPR003968Potassium channel, voltage dependent, Kv
IPR003972Potassium channel, voltage dependent, Kv1
IPR004049Potassium channel, voltage dependent, Kv1.2
IPR005821Ion transport domain
IPR011333SKP1/BTB/POZ domain
IPR027359Voltage-dependent channel, four helix bundle domain
IPR028325Voltage-gated potassium channel

No MapMan annotations defined for this gene.