Gene: ENSG00000177189 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000177189
Transcript Identifier
ENST00000379565
Gene Type
Coding gene
Location
X : 20155398-20266632 : negative

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P011657
(7 genes in 3 species)
specific family

Descriptions

gene_descr
ribosomal protein S6 kinase, 90kDa, polypeptide 3

Identifiers

Type Value
pidENSP00000368884
HGNC10432
UniprotP51812

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001501
TAS
Genome Projectskeletal system development
GO:0002224
ISS
TAS, IEA
Genome Projecttoll-like receptor signaling pathway
GO:0002755
TAS
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0006468
IBA
IEA
Genome Projectprotein phosphorylation
GO:0007049
IEA
Genome Projectcell cycle
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0007411
TAS
Genome Projectaxon guidance
GO:0007417
TAS
Genome Projectcentral nervous system development
GO:0016310
IEA
Genome Projectphosphorylation
GO:0030307
TAS
Genome Projectpositive regulation of cell growth
GO:0032496
ISS
IEA
Genome Projectresponse to lipopolysaccharide
GO:0034134
TAS
Genome Projecttoll-like receptor 2 signaling pathway
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0034146
TAS
Genome Projecttoll-like receptor 5 signaling pathway
GO:0034162
TAS
Genome Projecttoll-like receptor 9 signaling pathway
GO:0034166
TAS
Genome Projecttoll-like receptor 10 signaling pathway
GO:0035556
IBA
IEA
Genome Projectintracellular signal transduction
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0038123
TAS
Genome Projecttoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124
TAS
Genome Projecttoll-like receptor TLR6:TLR2 signaling pathway
GO:0043066
TAS
Genome Projectnegative regulation of apoptotic process
GO:0043154
IDA
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043555
TAS
Genome Projectregulation of translation in response to stress
GO:0043620
TAS
Genome Projectregulation of DNA-templated transcription in response to stress
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045597
TAS
Genome Projectpositive regulation of cell differentiation
GO:0045944
IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0051403
TAS
Genome Projectstress-activated MAPK cascade

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0000287
IEA
Genome Projectmagnesium ion binding
GO:0004672
TAS, IEA
Genome Projectprotein kinase activity
GO:0004674
TAS, IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004711
IBA
Genome Projectribosomal protein S6 kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0043027
IDA
Genome Projectcysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IBA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR016239Ribosomal protein S6 kinase II
IPR017441Protein kinase, ATP binding site
IPR017892Protein kinase, C-terminal

No MapMan annotations defined for this gene.