Gene: ENSG00000176749 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000176749
Transcript Identifier
ENST00000313401
Gene Type
Coding gene
Location
17 : 32487621-32488544 : positive

Family Information

Homologous gene family
HOM03P014024
(6 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P075357
(2 genes in 2 species)
specific family

Descriptions

gene_descr
cyclin-dependent kinase 5, regulatory subunit 1 (p35)

Identifiers

Type Value
pidENSP00000318486
HGNC1775
UniprotQ15078

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000079
TAS
Genome Projectregulation of cyclin-dependent protein serine/threonine kinase activity
GO:0001764
ISS
IEA
Genome Projectneuron migration
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007158
ISS
IEA
Genome Projectneuron cell-cell adhesion
GO:0007213
ISS
IEA
Genome ProjectG-protein coupled acetylcholine receptor signaling pathway
GO:0007411
ISS
TAS, IEA
Genome Projectaxon guidance
GO:0007413
ISS
IEA
Genome Projectaxonal fasciculation
GO:0007420
ISS
NAS, IEA
Genome Projectbrain development
GO:0008283
TAS
Genome Projectcell proliferation
GO:0009790
IEA
Genome Projectembryo development
GO:0018105
IDA
Genome Projectpeptidyl-serine phosphorylation
GO:0018107
IDA
Genome Projectpeptidyl-threonine phosphorylation
GO:0021549
IEA
Genome Projectcerebellum development
GO:0021722
IEA
Genome Projectsuperior olivary nucleus maturation
GO:0021766
IEA
Genome Projecthippocampus development
GO:0021799
IEA
Genome Projectcerebral cortex radially oriented cell migration
GO:0021819
IEA
Genome Projectlayer formation in cerebral cortex
GO:0030182
ISS
IEA
Genome Projectneuron differentiation
GO:0030517
IEA
Genome Projectnegative regulation of axon extension
GO:0031175
ISS
IEA
Genome Projectneuron projection development
GO:0032956
IEA
Genome Projectregulation of actin cytoskeleton organization
GO:0033136
IEA
Genome Projectserine phosphorylation of STAT3 protein
GO:0035235
ISS
IEA
Genome Projectionotropic glutamate receptor signaling pathway
GO:0043525
ISS
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0045664
NAS
Genome Projectregulation of neuron differentiation
GO:0045860
IEA
Genome Projectpositive regulation of protein kinase activity
GO:0045892
IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0048013
ISS
IEA
Genome Projectephrin receptor signaling pathway
GO:0048511
IEA
Genome Projectrhythmic process
GO:0061001
ISS
IEA
Genome Projectregulation of dendritic spine morphogenesis
GO:0070507
IEA
Genome Projectregulation of microtubule cytoskeleton organization
GO:0071158
IEA
Genome Projectpositive regulation of cell cycle arrest
GO:0071902
IDA
ISS
IEA
Genome Projectpositive regulation of protein serine/threonine kinase activity
GO:0090314
IEA
Genome Projectpositive regulation of protein targeting to membrane

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004672
TAS
Genome Projectprotein kinase activity
GO:0004693
IEA
Genome Projectcyclin-dependent protein serine/threonine kinase activity
GO:0005509
ISS
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0016301
ISS
IEA
Genome Projectkinase activity
GO:0016534
IEA
Genome Projectcyclin-dependent protein kinase 5 activator activity
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0043539
IDA
ISS
IEA
Genome Projectprotein serine/threonine kinase activator activity
GO:0045296
ISS
IEA
Genome Projectcadherin binding
GO:0046875
IEA
Genome Projectephrin receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISS
IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
ISS
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0014069
ISS
IEA
Genome Projectpostsynaptic density
GO:0016020
ISS
IEA
Genome Projectmembrane
GO:0016533
IEA
Genome Projectcyclin-dependent protein kinase 5 holoenzyme complex
GO:0030424
ISS
IEA
Genome Projectaxon
GO:0030425
ISS
IEA
Genome Projectdendrite
GO:0030426
ISS
IEA
Genome Projectgrowth cone
GO:0031594
ISS
IEA
Genome Projectneuromuscular junction
GO:0043025
ISS
IEA
Genome Projectneuronal cell body
GO:0043197
ISS
IEA
Genome Projectdendritic spine
GO:0043231
IDA
Genome Projectintracellular membrane-bounded organelle
GO:0043292
ISS
IEA
Genome Projectcontractile fiber
GO:0048471
IDA
IEA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004944Cyclin-dependent kinase 5 activator
IPR013763Cyclin-like

No MapMan annotations defined for this gene.