Gene: ENSG00000176105 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000176105
Transcript Identifier
ENST00000577961
Gene Type
Coding gene
Location
18 : 724424-775195 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P005517
(15 genes in 3 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
YES proto-oncogene 1, Src family tyrosine kinase

Identifiers

Type Value
pidENSP00000464380
HGNC12841
UniprotJ3QRU1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007169
IBA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0030154
IBA
Genome Projectcell differentiation
GO:0038083
IBA
Genome Projectpeptidyl-tyrosine autophosphorylation
GO:0042127
IBA
Genome Projectregulation of cell proliferation
GO:0045087
IBA
Genome Projectinnate immune response
GO:0071375
IBA
Genome Projectcellular response to peptide hormone stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004715
IEA
Genome Projectnon-membrane spanning protein tyrosine kinase activity
GO:0005102
IBA
Genome Projectreceptor binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005886
IDA
Genome Projectplasma membrane
GO:0031234
IBA
Genome Projectextrinsic component of cytoplasmic side of plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR000980SH2 domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001452SH3 domain
IPR008266Tyrosine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain
IPR028459Tyrosine-protein kinase Fgr

No MapMan annotations defined for this gene.