Gene: ENSG00000175595 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000175595
Transcript Identifier
ENST00000311895
Gene Type
Coding gene
Location
16 : 13920166-13948347 : positive

Family Information

Homologous gene family
HOM03P001995
(42 genes in 38 species)
specific family

Descriptions

gene_descr
excision repair cross-complementation group 4

Identifiers

Type Value
pidENSP00000310520
HGNC3436
UniprotQ92889

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000712
IBA
Genome Projectresolution of meiotic recombination intermediates
GO:0000718
TAS
Genome Projectnucleotide-excision repair, DNA damage removal
GO:0000723
IMP, IGI
Genome Projecttelomere maintenance
GO:0000724
IMP
Genome Projectdouble-strand break repair via homologous recombination
GO:0006259
IEA
Genome ProjectDNA metabolic process
GO:0006281
IMP, IGI
TAS, IEA
Genome ProjectDNA repair
GO:0006283
TAS
Genome Projecttranscription-coupled nucleotide-excision repair
GO:0006289
IDA, IMP
TAS
Genome Projectnucleotide-excision repair
GO:0006295
IMP
Genome Projectnucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296
IMP
Genome Projectnucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0009411
IMP
Genome Projectresponse to UV
GO:0009650
IEA
Genome ProjectUV protection
GO:0032205
IMP
Genome Projectnegative regulation of telomere maintenance
GO:0033683
IDA
Genome Projectnucleotide-excision repair, DNA incision
GO:0034644
IGI
Genome Projectcellular response to UV
GO:1901255
IBA
Genome Projectnucleotide-excision repair involved in interstrand cross-link repair

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000014
IBA
Genome Projectsingle-stranded DNA endodeoxyribonuclease activity
GO:0001094
IEA
Genome ProjectTFIID-class transcription factor binding
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003684
IMP
Genome Projectdamaged DNA binding
GO:0003697
IDA
Genome Projectsingle-stranded DNA binding
GO:0004518
IEA
Genome Projectnuclease activity
GO:0004519
IEA
Genome Projectendonuclease activity
GO:0004520
IDA, IMP
Genome Projectendodeoxyribonuclease activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0047485
IPI
Genome Projectprotein N-terminus binding
GO:0043566
IDA
Genome Projectstructure-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000109
IDA
Genome Projectnucleotide-excision repair complex
GO:0000110
IDA
Genome Projectnucleotide-excision repair factor 1 complex
GO:0000781
IDA
Genome Projectchromosome, telomeric region
GO:0000784
IDA
Genome Projectnuclear chromosome, telomeric region
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005669
IEA
Genome Projecttranscription factor TFIID complex
GO:0070522
IDA
Genome ProjectERCC4-ERCC1 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006166ERCC4 domain
IPR006167DNA repair protein
IPR010994RuvA domain 2-like
IPR011335Restriction endonuclease type II-like
IPR020819DNA repair nuclease, XPF-type/Helicase

No MapMan annotations defined for this gene.