Gene: ENSG00000174885 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000174885
Transcript Identifier
ENST00000312165
Gene Type
Coding gene
Location
11 : 278570-285304 : positive

Family Information

Homologous gene family
HOM03P001064
(59 genes in 4 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
NLR family, pyrin domain containing 6

Identifiers

Type Value
pidENSP00000309767
HGNC22944
UniprotP59044

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002862
IEA
Genome Projectnegative regulation of inflammatory response to antigenic stimulus
GO:0007186
ISS
Genome ProjectG-protein coupled receptor signaling pathway
GO:0009617
IEA
Genome Projectresponse to bacterium
GO:0010506
IEA
Genome Projectregulation of autophagy
GO:0034122
IEA
Genome Projectnegative regulation of toll-like receptor signaling pathway
GO:0042060
IEA
Genome Projectwound healing
GO:0043124
IEA
Genome Projectnegative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043409
IEA
Genome Projectnegative regulation of MAPK cascade
GO:0050727
ISS
IEA
Genome Projectregulation of inflammatory response
GO:0050777
IEA
Genome Projectnegative regulation of immune response
GO:0070255
IEA
Genome Projectregulation of mucus secretion
GO:0070373
IEA
Genome Projectnegative regulation of ERK1 and ERK2 cascade

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0005000
ISS
Genome Projectvasopressin receptor activity
GO:0005524
IEA
Genome ProjectATP binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0031965
IEA
Genome Projectnuclear membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR004020DAPIN domain
IPR007111NACHT nucleoside triphosphatase
IPR011029Death-like domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.