Gene: ENSG00000173511 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000173511
Transcript Identifier
ENST00000309422
Gene Type
Coding gene
Location
11 : 64234834-64237633 : positive

Family Information

Homologous gene family
HOM03P016811
(5 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P064873
(2 genes in 2 species)
specific family

Descriptions

gene_descr
vascular endothelial growth factor B

Identifiers

Type Value
pidENSP00000311127
HGNC12681
UniprotP49765
UniprotQ7LAP4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001938
IDA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0002576
TAS
Genome Projectplatelet degranulation
GO:0006493
IEA
Genome Projectprotein O-linked glycosylation
GO:0007507
IEA
Genome Projectheart development
GO:0007596
TAS
Genome Projectblood coagulation
GO:0010629
IDA
Genome Projectnegative regulation of gene expression
GO:0030168
TAS
Genome Projectplatelet activation
GO:0030949
IDA
Genome Projectpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0035470
IDA
Genome Projectpositive regulation of vascular wound healing
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043066
IDA
Genome Projectnegative regulation of apoptotic process
GO:0043524
IDA
Genome Projectnegative regulation of neuron apoptotic process
GO:0048010
TAS
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0050731
IDA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050918
IDA
Genome Projectpositive chemotaxis
GO:0050930
IDA
Genome Projectinduction of positive chemotaxis
GO:0051781
IEA
Genome Projectpositive regulation of cell division
GO:0051897
IDA
Genome Projectpositive regulation of protein kinase B signaling
GO:0060048
IEA
Genome Projectcardiac muscle contraction
GO:0060754
IDA
Genome Projectpositive regulation of mast cell chemotaxis
GO:0060976
IEA
Genome Projectcoronary vasculature development
GO:0070374
IDA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0043117
IDA
Genome Projectpositive regulation of vascular permeability

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008083
IEA
Genome Projectgrowth factor activity
GO:0008201
IEA
Genome Projectheparin binding
GO:0042056
IDA
Genome Projectchemoattractant activity
GO:0042803
IEA
Genome Projectprotein homodimerization activity
GO:0043183
IPI
Genome Projectvascular endothelial growth factor receptor 1 binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
Genome Projectextracellular space
GO:0005622
IEA
Genome Projectintracellular
GO:0016020
IEA
Genome Projectmembrane
GO:0031093
TAS
Genome Projectplatelet alpha granule lumen

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000072PDGF/VEGF domain
IPR023581Platelet-derived growth factor, conserved site
IPR029034Cystine-knot cytokine

No MapMan annotations defined for this gene.