Gene: ENSG00000173221 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000173221
Transcript Identifier
ENST00000512469
Gene Type
Coding gene
Location
5 : 95816513-95822662 : negative

Family Information

Homologous gene family
HOM03P000214
(164 genes in 34 species)
specific family
Orthologous gene family
ORTHO03P003834
(22 genes in 20 species)
specific family

Descriptions

gene_descr
glutaredoxin (thioltransferase)

Identifiers

Type Value
pidENSP00000424636
HGNC4330
UniprotP35754
UniprotA0A024RAM2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008152
IEA
Genome Projectmetabolic process
GO:0045454
IEA
Genome Projectcell redox homeostasis
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0015949
TAS
Genome Projectnucleobase-containing small molecule interconversion
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045838
IDA
Genome Projectpositive regulation of membrane potential
GO:0055086
TAS
Genome Projectnucleobase-containing small molecule metabolic process
GO:0080058
TAS
Genome Projectprotein deglutathionylation
GO:2000651
IDA
Genome Projectpositive regulation of sodium ion transmembrane transporter activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009055
IEA
Genome Projectelectron carrier activity
GO:0015035
IEA
Genome Projectprotein disulfide oxidoreductase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0015038
TAS
Genome Projectglutathione disulfide oxidoreductase activity
GO:0047485
IPI
Genome Projectprotein N-terminus binding
GO:0097573
TAS
Genome Projectglutathione oxidoreductase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005829
TAS
Genome Projectcytosol
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002109Glutaredoxin
IPR011767Glutaredoxin active site
IPR011899Glutaredoxin, eukaryotic/virial
IPR012336Thioredoxin-like fold
IPR014025Glutaredoxin subgroup

No MapMan annotations defined for this gene.