Gene: ENSG00000172936 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000172936
Transcript Identifier
ENST00000417037
Gene Type
Coding gene
Location
3 : 38138662-38141286 : positive

Family Information

Homologous gene family
HOM03P035896
(2 genes in 2 species)
specific family

Descriptions

gene_descr
myeloid differentiation primary response 88

Identifiers

Type Value
pidENSP00000401399
HGNC7562
UniprotA0A0A0MST0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002238
IEA
Genome Projectresponse to molecule of fungal origin
GO:0002376
IEA
Genome Projectimmune system process
GO:0002755
IEA
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007254
IEA
Genome ProjectJNK cascade
GO:0008063
IEA
Genome ProjectToll signaling pathway
GO:0009615
IEA
Genome Projectresponse to virus
GO:0016064
IEA
Genome Projectimmunoglobulin mediated immune response
GO:0019221
IEA
Genome Projectcytokine-mediated signaling pathway
GO:0031663
IEA
Genome Projectlipopolysaccharide-mediated signaling pathway
GO:0032494
IEA
Genome Projectresponse to peptidoglycan
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032740
IEA
Genome Projectpositive regulation of interleukin-17 production
GO:0032747
IEA
Genome Projectpositive regulation of interleukin-23 production
GO:0032755
IEA
Genome Projectpositive regulation of interleukin-6 production
GO:0032760
IEA
Genome Projectpositive regulation of tumor necrosis factor production
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0043123
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044130
IEA
Genome Projectnegative regulation of growth of symbiont in host
GO:0045080
IEA
Genome Projectpositive regulation of chemokine biosynthetic process
GO:0045351
IEA
Genome Projecttype I interferon biosynthetic process
GO:0046330
IEA
Genome Projectpositive regulation of JNK cascade
GO:0048661
IEA
Genome Projectpositive regulation of smooth muscle cell proliferation
GO:0050671
IEA
Genome Projectpositive regulation of lymphocyte proliferation
GO:0050727
IEA
Genome Projectregulation of inflammatory response
GO:0050830
IEA
Genome Projectdefense response to Gram-positive bacterium
GO:0051092
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0090557
IEA
Genome Projectestablishment of endothelial intestinal barrier

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005121
IEA
Genome ProjectToll binding
GO:0005149
IEA
Genome Projectinterleukin-1 receptor binding
GO:0070976
IEA
Genome ProjectTIR domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0043234
IEA
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000157Toll/interleukin-1 receptor homology (TIR) domain
IPR000488Death domain
IPR011029Death-like domain
IPR017281Myeloid differentiation primary response protein MyD88

No MapMan annotations defined for this gene.