Gene: ENSG00000172572 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000172572
Transcript Identifier
ENST00000359062
Gene Type
Coding gene
Location
12 : 20369285-20680271 : positive

Family Information

Homologous gene family
HOM03P000134
(221 genes in 29 species)
specific family
Orthologous gene family
ORTHO03P023344
(4 genes in 3 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
phosphodiesterase 3A, cGMP-inhibited

Identifiers

Type Value
pidENSP00000351957
HGNC8778
UniprotQ14432

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001556
IEA
Genome Projectoocyte maturation
GO:0006198
IDA, IMP
IEA
Genome ProjectcAMP catabolic process
GO:0006629
TAS
Genome Projectlipid metabolic process
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007596
TAS
Genome Projectblood coagulation
GO:0016101
IEA
Genome Projectditerpenoid metabolic process
GO:0019933
IMP
Genome ProjectcAMP-mediated signaling
GO:0019934
IMP
Genome ProjectcGMP-mediated signaling
GO:0040020
IEA
Genome Projectregulation of meiotic nuclear division
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043116
IMP
Genome Projectnegative regulation of vascular permeability
GO:0043117
IMP
Genome Projectpositive regulation of vascular permeability
GO:0051591
IEA
Genome Projectresponse to cAMP
GO:0060282
IEA
Genome Projectpositive regulation of oocyte development
GO:0071321
IDA
Genome Projectcellular response to cGMP
GO:0071560
IEP
Genome Projectcellular response to transforming growth factor beta stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004114
IEA
Genome Project3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115
IEA
Genome Project3',5'-cyclic-AMP phosphodiesterase activity
GO:0004119
TAS, IEA
Genome ProjectcGMP-inhibited cyclic-nucleotide phosphodiesterase activity
GO:0008081
IEA
Genome Projectphosphoric diester hydrolase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0030552
IEA
Genome ProjectcAMP binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domain
IPR003607HD/PDEase domain
IPR0231743'5'-cyclic nucleotide phosphodiesterase, conserved site

No MapMan annotations defined for this gene.