Gene: ENSG00000172216 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000172216
Transcript Identifier
ENST00000303004
Gene Type
Coding gene
Location
20 : 50191034-50192071 : positive

Family Information

Homologous gene family
HOM03P008491
(10 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P072061
(2 genes in 2 species)
specific family

Descriptions

gene_descr
CCAAT/enhancer binding protein (C/EBP), beta

Identifiers

Type Value
pidENSP00000305422
HGNC1834
UniprotP17676

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001541
ISS
IEA
Genome Projectovarian follicle development
GO:0001892
IEA
Genome Projectembryonic placenta development
GO:0002432
ISS
IEA
Genome Projectgranuloma formation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IDA
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
TAS, IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006953
TAS
Genome Projectacute-phase response
GO:0006954
TAS
Genome Projectinflammatory response
GO:0006955
TAS
Genome Projectimmune response
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030182
IEA
Genome Projectneuron differentiation
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032753
ISS
IEA
Genome Projectpositive regulation of interleukin-4 production
GO:0033598
IEA
Genome Projectmammary gland epithelial cell proliferation
GO:0034976
IDA
Genome Projectresponse to endoplasmic reticulum stress
GO:0035711
ISS
IEA
Genome ProjectT-helper 1 cell activation
GO:0042130
ISS
IEA
Genome Projectnegative regulation of T cell proliferation
GO:0042742
ISS
IEA
Genome Projectdefense response to bacterium
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045408
IEA
Genome Projectregulation of interleukin-6 biosynthetic process
GO:0045444
IEA
Genome Projectfat cell differentiation
GO:0045600
ISS
IEA
Genome Projectpositive regulation of fat cell differentiation
GO:0045669
IEA
Genome Projectpositive regulation of osteoblast differentiation
GO:0045670
ISS
IEA
Genome Projectregulation of osteoclast differentiation
GO:0045892
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0050873
IEA
Genome Projectbrown fat cell differentiation
GO:0060644
IEA
Genome Projectmammary gland epithelial cell differentiation
GO:0060850
ISS
IEA
Genome Projectregulation of transcription involved in cell fate commitment
GO:0070059
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071230
IEA
Genome Projectcellular response to amino acid stimulus
GO:0072574
ISS
IEA
Genome Projecthepatocyte proliferation
GO:0097421
ISS
IEA
Genome Projectliver regeneration
GO:1990440
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IDA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003677
TAS, IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
NAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
ISS
IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IEA
Genome Projecttranscription factor binding
GO:0019900
IEA
Genome Projectkinase binding
GO:0035035
IEA
Genome Projecthistone acetyltransferase binding
GO:0035259
IEA
Genome Projectglucocorticoid receptor binding
GO:0042803
ISS
IEA
Genome Projectprotein homodimerization activity
GO:0042826
IEA
Genome Projecthistone deacetylase binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044389
IEA
Genome Projectubiquitin-like protein ligase binding
GO:0046982
NAS, IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000779
IEA
Genome Projectcondensed chromosome, centromeric region
GO:0000790
IEA
Genome Projectnuclear chromatin
GO:0005634
IDA
TAS, IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IEA
Genome Projectcytoplasm
GO:0016363
IEA
Genome Projectnuclear matrix
GO:0036488
NAS, IEA
Genome ProjectCHOP-C/EBP complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004827Basic-leucine zipper domain
IPR016468CCAAT/enhancer-binding protein, chordates
IPR031106CCAAT/enhancer-binding protein C/EBP

No MapMan annotations defined for this gene.