Gene: ENSG00000171867 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000171867
Transcript Identifier
ENST00000430350
Gene Type
Coding gene
Location
20 : 4699221-4699982 : positive

Family Information

Homologous gene family
HOM03P094761
(orphan gene)
specific family

Descriptions

gene_descr
prion protein

Identifiers

Type Value
pidENSP00000399376
HGNC9449
UniprotP04156
UniprotQ53YK7

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001933
ISS
IEA
Genome Projectnegative regulation of protein phosphorylation
GO:0006878
NAS
Genome Projectcellular copper ion homeostasis
GO:0006979
ISS
IEA
Genome Projectresponse to oxidative stress
GO:0007049
IEA
Genome Projectcell cycle
GO:0007050
IEA
Genome Projectcell cycle arrest
GO:0007411
TAS
Genome Projectaxon guidance
GO:0007611
IEA
Genome Projectlearning or memory
GO:0008152
TAS
Genome Projectmetabolic process
GO:0032689
ISS
IEA
Genome Projectnegative regulation of interferon-gamma production
GO:0032700
ISS
IEA
Genome Projectnegative regulation of interleukin-17 production
GO:0032703
ISS
IEA
Genome Projectnegative regulation of interleukin-2 production
GO:0032880
IEA
Genome Projectregulation of protein localization
GO:0035690
IEA
Genome Projectcellular response to drug
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043433
ISS
IEA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0046007
ISS
IEA
Genome Projectnegative regulation of activated T cell proliferation
GO:0046686
IEA
Genome Projectresponse to cadmium ion
GO:0046688
IEA
Genome Projectresponse to copper ion
GO:0050860
ISS
IEA
Genome Projectnegative regulation of T cell receptor signaling pathway
GO:0051260
IEA
Genome Projectprotein homooligomerization
GO:0070885
ISS
IEA
Genome Projectnegative regulation of calcineurin-NFAT signaling cascade
GO:0071280
IDA
Genome Projectcellular response to copper ion
GO:1901379
IEA
Genome Projectregulation of potassium ion transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005507
IDA
TAS
Genome Projectcopper ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008017
IDA
Genome Projectmicrotubule binding
GO:0015631
IDA
Genome Projecttubulin binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0043008
IEA
Genome ProjectATP-dependent protein binding
GO:0044325
IEA
Genome Projection channel binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051087
IEA
Genome Projectchaperone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
TAS, IEA
Genome Projectcytoplasm
GO:0005783
ISS
IEA
Genome Projectendoplasmic reticulum
GO:0005794
ISS
IEA
Genome ProjectGolgi apparatus
GO:0005886
IDA
ISS
IEA
Genome Projectplasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0019898
TAS
Genome Projectextrinsic component of membrane
GO:0031225
IEA
Genome Projectanchored component of membrane
GO:0045121
IDA
ISS
IEA
Genome Projectmembrane raft
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000817Prion protein
IPR022416Prion/Doppel protein, beta-ribbon domain
IPR025860Major prion protein N-terminal domain

No MapMan annotations defined for this gene.