Gene: ENSG00000171860 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000171860
Transcript Identifier
ENST00000307637
Gene Type
Coding gene
Location
12 : 8058737-8060185 : negative

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P070334
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
complement component 3a receptor 1

Identifiers

Type Value
pidENSP00000302079
HGNC1319
UniprotQ16581
UniprotA8K2H7

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002430
IEA
Genome Projectcomplement receptor mediated signaling pathway
GO:0002462
IEA
Genome Projecttolerance induction to nonself antigen
GO:0006935
IEA
Genome Projectchemotaxis
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
TAS, IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007204
IGI
TAS, IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0008217
IEA
Genome Projectregulation of blood pressure
GO:0010575
IEA
Genome Projectpositive regulation of vascular endothelial growth factor production
GO:0010759
IEA
Genome Projectpositive regulation of macrophage chemotaxis
GO:0030335
IEA
Genome Projectpositive regulation of cell migration
GO:0045766
IEA
Genome Projectpositive regulation of angiogenesis
GO:0048661
IEA
Genome Projectpositive regulation of smooth muscle cell proliferation
GO:0072126
IEA
Genome Projectpositive regulation of glomerular mesangial cell proliferation
GO:0090023
IEA
Genome Projectpositive regulation of neutrophil chemotaxis
GO:2000573
IEA
Genome Projectpositive regulation of DNA biosynthetic process
GO:0006954
TAS
Genome Projectinflammatory response
GO:0008015
TAS
Genome Projectblood circulation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001850
IEA
Genome Projectcomplement component C3a binding
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IGI
TAS, IEA
Genome ProjectG-protein coupled receptor activity
GO:0004942
IEA
Genome Projectanaphylatoxin receptor activity
GO:0004943
TAS, IEA
Genome ProjectC3a anaphylatoxin receptor activity
GO:0004435
TAS
Genome Projectphosphatidylinositol phospholipase C activity
GO:0004876
TAS
Genome Projectcomplement component C3a receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IGI
TAS, IEA
Genome Projectcytosol
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000826Formyl peptide receptor-related
IPR001644C3a anaphylatoxin chemotactic receptor
IPR002234Anaphylatoxin chemotactic receptor family
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.